Regular Article

Central line bloodstream infections can be reduced in newborn infants using the modified Seldinger technique and care bundles of preventative measures

Corresponding Author

IJJ Arnts

Department of Neonatology, Radboud University Medical Centre, Nijmegen, The Netherlands

Correspondence

I.J.J. Arnts, Department of Neonatology, Radboud University Medical Centre Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

Tel: +31243613860/+31243668120|

Fax: +31243619123|

Email: [email protected]

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NM Schrijvers,

NM Schrijvers

Department of Neonatology, Radboud University Medical Centre, Nijmegen, The Netherlands

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M van der Flier,

M van der Flier

Department of Pediatrics, and Nijmegen Institute for Infection, Inflammation and Immunity, Radboud University Medical Centre, Nijmegen, The Netherlands

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JMM Groenewoud,

JMM Groenewoud

Department for Health Evidence, Radboud University Medical Centre, Nijmegen, The Netherlands

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T Antonius,

T Antonius

Department of Neonatology, Radboud University Medical Centre, Nijmegen, The Netherlands

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KD Liem,

KD Liem

Department of Neonatology, Radboud University Medical Centre, Nijmegen, The Netherlands

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IJJ Arnts,

Corresponding Author

IJJ Arnts

Department of Neonatology, Radboud University Medical Centre, Nijmegen, The Netherlands

Correspondence

I.J.J. Arnts, Department of Neonatology, Radboud University Medical Centre Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

Tel: +31243613860/+31243668120|

Fax: +31243619123|

Email: [email protected]

Search for more papers by this author

NM Schrijvers,

NM Schrijvers

Department of Neonatology, Radboud University Medical Centre, Nijmegen, The Netherlands

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M van der Flier,

M van der Flier

Department of Pediatrics, and Nijmegen Institute for Infection, Inflammation and Immunity, Radboud University Medical Centre, Nijmegen, The Netherlands

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JMM Groenewoud,

JMM Groenewoud

Department for Health Evidence, Radboud University Medical Centre, Nijmegen, The Netherlands

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T Antonius,

T Antonius

Department of Neonatology, Radboud University Medical Centre, Nijmegen, The Netherlands

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KD Liem,

KD Liem

Department of Neonatology, Radboud University Medical Centre, Nijmegen, The Netherlands

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First published: 26 December 2014

https://doi.org/10.1111/apa.12915

Citations: 16

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Abstract

Aim

There has been no evidence to show whether care bundles of preventive measures reduce central line-associated bloodstream infection (CLABSI) in peripherally inserted central catheters using the modified Seldinger technique, which requires more specific skills than the traditional technique. The aim of this study was to address that gap in our knowledge and to determine whether other variables influenced the outcome.

Methods

This prospective observational study was conducted on a neonatal intensive care unit. We observed the incidence of CLABSI in 45 newborn infants with peripheral catheters before the introduction of bundles of preventative measures and 88 infants after the introduction.

Results

Laboratory-confirmed CLABSI decreased after the introduction of the bundles, from 12.9 per 1000 days to 4.7/1000 days (p = 0.09). When we combined the rates for laboratory-confirmed CLABSI and clinical CLABSI in a survival analysis, the incidence reduced significantly after introduction of the bundles (p = 0.02). There were no other variables that affected the outcome.

Conclusion

Cost-effective care bundles reduced CLABSI in peripherally inserted central catheters using the modified Seldinger technique, despite the specific insertion skills that were required. The bundles of preventative measures may increase healthcare professionals’ awareness of the need to care for central catheters and reduce CLABSI infections.

Graphical Abstract

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Citing Literature

Volume104, Issue4

April 2015

Pages e152-e157