Rapid quantification of sputum eosinophil peroxidase on a lateral flow test strip
M. G. Wolfe
Biointerfaces Institute, McMaster University, Hamilton, ON, Canada
Search for more papers by this authorM. Mukherjee
Department of Medicine Hamilton, Firestone Institute for Respiratory Health, St. Joseph's Healthcare, Hamilton and McMaster University, ON, Canada
Search for more papers by this authorK. Radford
Department of Medicine Hamilton, Firestone Institute for Respiratory Health, St. Joseph's Healthcare, Hamilton and McMaster University, ON, Canada
Search for more papers by this authorJ. D. Brennan
Biointerfaces Institute, McMaster University, Hamilton, ON, Canada
Search for more papers by this authorCorresponding Author
P. Nair
Department of Medicine Hamilton, Firestone Institute for Respiratory Health, St. Joseph's Healthcare, Hamilton and McMaster University, ON, Canada
Correspondence
Parameswaran Nair, Firestone Institute for Respiratory Health, St. Joseph's Healthcare Hamilton, 50 Charlton Avenue East, Hamilton, ON L8N 4A6, Canada. Email: [email protected]
Search for more papers by this authorM. G. Wolfe
Biointerfaces Institute, McMaster University, Hamilton, ON, Canada
Search for more papers by this authorM. Mukherjee
Department of Medicine Hamilton, Firestone Institute for Respiratory Health, St. Joseph's Healthcare, Hamilton and McMaster University, ON, Canada
Search for more papers by this authorK. Radford
Department of Medicine Hamilton, Firestone Institute for Respiratory Health, St. Joseph's Healthcare, Hamilton and McMaster University, ON, Canada
Search for more papers by this authorJ. D. Brennan
Biointerfaces Institute, McMaster University, Hamilton, ON, Canada
Search for more papers by this authorCorresponding Author
P. Nair
Department of Medicine Hamilton, Firestone Institute for Respiratory Health, St. Joseph's Healthcare, Hamilton and McMaster University, ON, Canada
Correspondence
Parameswaran Nair, Firestone Institute for Respiratory Health, St. Joseph's Healthcare Hamilton, 50 Charlton Avenue East, Hamilton, ON L8N 4A6, Canada. Email: [email protected]
Search for more papers by this author
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REFERENCES
- 1Jayaram L, Pizzichini MM, Cook RJ, et al. Determining asthma treatment by monitoring sputum cell counts: effect on exacerbations. Eur Respir J. 2006; 27: 483-494.
- 2Siva R, Green RH, Brightling CE, et al. Eosinophilic airway inflammation and exacerbations of COPD: a randomised controlled trial. Eur Respir J. 2007; 29: 906-913.
- 3Wolfe MG, Zhang Q, Hui C, et al. Development of a functional point-of-need diagnostic for myeloperoxidase detection to identify neutrophilic bronchitis. Analyst. 2016; 141: 6438-6443.
- 4Nair P, Ochkur SI, Protheroe C, et al. Eosinophil peroxidase in sputum represents a unique biomarker of airway eosinophilia. Allergy. 2013; 68: 1177-1184.
- 5Ochkur SI, Kim JD, Protheroe CA, et al. A sensitive high throughput ELISA for human eosinophil peroxidase: A specific assay to quantify eosinophil degranulation from patient-derived sources. J Immunol Methods. 2012; 384: 10-20.
- 6Nair P, Zhang Q, Brennan JD. A perspective on point-of-care tests to detect eosinophilic bronchitis. J Asthma. 2015; 52: 254-261.
- 7Nair P, Hargreave FE. Measuring bronchitis in airway diseases: clinical implementation and application: Airway hyperresponsiveness in asthma: its measurement and clinical significance. Chest. 2010; 138(2 Suppl): 38S-43S.
- 8Belda J, Leigh R, Parameswaran K, et al. Induced Sputum Cell Counts in Healthy Adults. Am J Respir Crit Care Med. 2000; 161: 475-478.
- 9Mukherjee M, Bulir DC, Radford K, et al. Sputum autoantibodies in patients with severe eosinophilic asthma. J Allergy Clin Immunol. 2018; 141: 1269-1279.