Corrigendum

Shin JU, Kim SH, Noh JY, Kim JH, Kim HR, Jeong KY, Park KH, Lee J, Chu H, Lee JH, Yong TS, Park JW, Lee KH. Allergen-specific immunotherapy induces regulatory T cells in an atopic dermatitis mouse model. Allergy. 2018;73(9):1801-1811.

In the article, Figure 1i is corrected with the data showing serum concentrations of mouse IgG2a instead of IgG4 that does not exist in mice. The reported data, as measured using the human IgG4 ELISA kit, may be caused by cross-reactivity between the anti-IgG4 antibody and the murine IgG2a.

The new Figure 1i shows total IgG2a, which was analyzed using a mouse IgG2a ELISA kit in the serum samples of mice at different time points.

In the legend of Figure 1 on 1803, line 7, the following has been erroneously stated: “(I) IgG4 were analyzed by performing ELISA on sera at different time points” That sentence should read: “(I) total IgG2a was analyzed by performing ELISA on sera at different time points.”

Page 1801, line 15 in the abstract should be deleted: “Also, SIT induced the immunoglobulin G4 and attenuated allergen-specific immunoglobulin E.”

In the section 2.5, on page 1802, line 51 and 52, the following has been erroneously stated: “IgG4 was measured using an IgG4 ELISA Kit (MyBioSource, San Diego, CA, USA).” That sentence should be corrected with “IgG2a was measured using an IgG2a ELISA Kit (Invitrogen, Carlsbad, CA, USA).”

In the section 3.2 on page 1805 line 6, 9, and 10, the following has been erroneously stated: “so we measured total IgE, total IgG4,” “Total IgG4 level began increasing at week 4 and continuously increased throughout the entire SIT period (Figure 1I).” This should read: “so we measured total IgE and total IgG2a” in serum samples, “Total IgG2a level was significantly increased in SIT group between week 4 and 6 (Figure 1I).”

In the section 4 on page 1808, lines 52 and 53, the following has been erroneously stated: “Among the IgG isotypes, IgG4 has been implicated as a main effector of SIT in both number and function.^39,40 Similarly, in our study, the increase in total IgE was attenuated and the IgG4 level was increased after the initiation of SIT.” That sentence should read: “Among the IgG isotypes, IgG4 has been implicated as a main effector of SIT in both number and function in human studies.^39,40 In the mouse, although there is no full equivalent of human IgG4,⁴¹ increased serum IgG2 was reported after SIT.41, 42 Similarly, in our study, the increase of total IgE was attenuated and the IgG2a level was increased after the initiation of SIT.”

These corrections do not change the major findings or conclusions of the study. The authors apologize to the journal and the readers for any confusion that this inadvertent error may have caused.