The blood flow rate on the first day after arteriovenous fistula creation is a predictor of successful fistula maturation
Corresponding Author
Nikola Gjorgjievski
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Hospital of Nephrology, Skopje, North Macedonia
Correspondence
Nikola Gjorgjievski, University Hospital of Nephrology, Mother Teresa 17, Skopje, North Macedonia.
Email: [email protected]
Search for more papers by this authorPavlina Dzekova-Vidimliski
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Hospital of Nephrology, Skopje, North Macedonia
Search for more papers by this authorDragan Cibrev
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Hospital of Neurology, Skopje, North Macedonia
Search for more papers by this authorIrena Rambabova-Bushljetik
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Hospital of Nephrology, Skopje, North Macedonia
Search for more papers by this authorPetar Dejanov
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Hospital of Nephrology, Skopje, North Macedonia
Search for more papers by this authorGjulshen Selim
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Hospital of Nephrology, Skopje, North Macedonia
Search for more papers by this authorAna Stojanoska Severova
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Hospital of Nephrology, Skopje, North Macedonia
Search for more papers by this authorLada Trajceska
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Hospital of Nephrology, Skopje, North Macedonia
Search for more papers by this authorJulija Gjorgievska
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Clinic for Pediatric Diseases, Skopje, North Macedonia
Search for more papers by this authorVlatko Karanfilovski
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Hospital of Nephrology, Skopje, North Macedonia
Search for more papers by this authorGoce Spasovski
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Hospital of Nephrology, Skopje, North Macedonia
Search for more papers by this authorIgor G Nikolov
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Hospital of Nephrology, Skopje, North Macedonia
Search for more papers by this authorCorresponding Author
Nikola Gjorgjievski
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Hospital of Nephrology, Skopje, North Macedonia
Correspondence
Nikola Gjorgjievski, University Hospital of Nephrology, Mother Teresa 17, Skopje, North Macedonia.
Email: [email protected]
Search for more papers by this authorPavlina Dzekova-Vidimliski
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Hospital of Nephrology, Skopje, North Macedonia
Search for more papers by this authorDragan Cibrev
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Hospital of Neurology, Skopje, North Macedonia
Search for more papers by this authorIrena Rambabova-Bushljetik
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Hospital of Nephrology, Skopje, North Macedonia
Search for more papers by this authorPetar Dejanov
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Hospital of Nephrology, Skopje, North Macedonia
Search for more papers by this authorGjulshen Selim
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Hospital of Nephrology, Skopje, North Macedonia
Search for more papers by this authorAna Stojanoska Severova
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Hospital of Nephrology, Skopje, North Macedonia
Search for more papers by this authorLada Trajceska
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Hospital of Nephrology, Skopje, North Macedonia
Search for more papers by this authorJulija Gjorgievska
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Clinic for Pediatric Diseases, Skopje, North Macedonia
Search for more papers by this authorVlatko Karanfilovski
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Hospital of Nephrology, Skopje, North Macedonia
Search for more papers by this authorGoce Spasovski
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Hospital of Nephrology, Skopje, North Macedonia
Search for more papers by this authorIgor G Nikolov
Faculty of Medicine, SS “Cyril and Methodius”, Skopje, North Macedonia
University Hospital of Nephrology, Skopje, North Macedonia
Search for more papers by this authorClinical trial registration: The study was performed at the University Hospital of Nephrology, Skopje, N. Macedonia from January 2019 to March 2020.
Abstract
Background
The determination of blood flow rate (BFR) is a useful tool for assessing the function of arteriovenous fistula (AVF).
Methods
Eighty patients with a newly created radio cephalic AVF were analyzed. Hemodynamics and morphological characteristics of the blood vessels were assessed by Doppler ultrasound.
Results
The mean age of patients was 59.9 ± 13.5 years. A successful rate of AVF maturation was 62.5% at 8 weeks. Six adjusted models of multivariate analysis showed that BFR at Day 1 was a predictor for AVF maturation both at 4 weeks (p < 0.001) and 8 weeks (p < 0.001). Receiver operating characteristic analysis showed an optimal cut-off point for BFR at Day 1 of 395 ml/min for successful maturation at 4 weeks (sensitivity 0.714, specificity 0.889) and 344 ml/min for successful maturation at 8 weeks (sensitivity 0.860, specificity 0.867).
Conclusion
BFR at Day 1 is a powerful predictor for successful AVF maturation at 4 and 8 weeks.
CONFLICT OF INTEREST
The authors declare no conflict of interest.
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