Volume 58, Issue 4 pp. 1047-1049
Technical Note

Accuracy and Usefulness of the AVOXimeter 4000 as Routine Analysis of Carboxyhemoglobin

Junko Fujihara Ph.D.

Junko Fujihara Ph.D.

Department of Legal Medicine, Shimane University School of Medicine, 89-1 Enya, Izumo Shimane, 693-8501, Japan

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Hiroshi Kinoshita M.D., Ph.D.

Hiroshi Kinoshita M.D., Ph.D.

Department of Forensic Medicine, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kida-gun, Kagawa, 761-0793, Japan

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Naoko Tanaka B.S.

Naoko Tanaka B.S.

Department of Forensic Medicine, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kida-gun, Kagawa, 761-0793, Japan

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Toshihiro Yasuda Ph.D.

Toshihiro Yasuda Ph.D.

Division of Medical Genetics and Biochemistry, Faculty of Medical Sciences, University of Fukui, 23-3, Matsuokashimoaizuki, eiheiji-cho, Yoshida-gun, Fukui, 910-1193, Japan

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Haruo Takeshita M.D., Ph.D.

Corresponding Author

Haruo Takeshita M.D., Ph.D.

Department of Legal Medicine, Shimane University School of Medicine, 89-1 Enya, Izumo Shimane, 693-8501, Japan

Additional information and reprint requests:

Haruo Takeshita, M.D., Ph.D.

Department of Legal Medicine

Shimane University School of Medicine

89-1 Enya, Izumo

Shimane 693-8501

Japan

E-mail: [email protected]

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First published: 28 March 2013
Citations: 12
Supported in part by Grants-in-Aid from the Japan Society for the Promotion of Science (21590736 to JF).

Abstract

The measurement of blood carboxyhemoglobin (CO-Hb) is important to determine the cause of death. The AVOXimeter 4000 (AVOX), a portable CO-oximeter, has the advantages of a low purchase price and operating cost, ease of operation, and rapid results. Little information is available on the usefulness of AVOX in the forensic sample, and the previous study investigated only six samples. Therefore, in this study, we confirmed the usefulness of the AVOX through a comparison of its results with data previously obtained using the double wavelength spectrophotometric method in autopsies. Regression analysis was performed between CO-Hb levels measured by the AVOX and those measured by the conventional double wavelength spectrophotometric method in postmortem blood samples: a significant correlation was observed. This study suggests the usefulness of the AVOX to analyze postmortem blood, and the AVOX is suitable for routine forensic analysis and can be applied at the crime scene.

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