Increased circulating interleukin 36γ DNA copies in psoriasis
Kazumi Urata
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorTselmeg Mijiddorj Myangat
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorCorresponding Author
Ikko Kajihara
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Correspondence
Ikko Kajihara, Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556 Japan.
Email: [email protected]
Search for more papers by this authorSoichiro Sawamura
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorKatsunari Makino
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorShinichi Masuguchi
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorSatoshi Fukushima
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorKazumi Urata
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorTselmeg Mijiddorj Myangat
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorCorresponding Author
Ikko Kajihara
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Correspondence
Ikko Kajihara, Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556 Japan.
Email: [email protected]
Search for more papers by this authorSoichiro Sawamura
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorKatsunari Makino
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorShinichi Masuguchi
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorSatoshi Fukushima
Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan
Search for more papers by this authorKazumi Urata and Tselmeg Mijiddorj Myangat contributed equally to this study.
REFERENCES
- 1Dinarello CA. Interleukin-1 in the pathogenesis and treatment of inflammatory diseases. Blood. 2011; 117: 3720–3732.
- 2Sawamura S, Kajihara I, Sakamoto R, Otsuka-Maeda S, Kanemaru H, Kanazawa-Yamada S, et al. Elevation of circulating interleukin-23 DNA levels in patients with psoriasis. J Dermatol. 2022; 49: e295–e296.
- 3Sachen KL, Arnold Greving CN, Towne JE. Role of IL-36 cytokines in psoriasis and other inflammatory skin conditions. Cytokine. 2022; 156:155897.
- 4Angero M, Dagmar W, Julia W, Michael H, Sandra F-S, Sonja S, et al. IL-36gamma (IL-1F9) is a biomarker for psoriasis skin lesions. J Invest Dermatol. 2015; 135: 1025–1032.
- 5Johnston A, Xing X, Guzman AM, Riblett MB, Loyd CM, Ward NL, et al. IL-1F5, -F6, -F8, and -F9: a novel IL-1 family signaling system that is active in psoriasis and promotes keratinocyte antimicrobial peptide expression. J Immunol. 2011; 186: 2613–2622.
