Methyl 1-benzoyl-3-hydroxy-4-methoxy-1,2,3,4-tetrahydroquinoline-2-carboxylate
Abstract
The title compound, C19H19NO5, is the result of a regioselective nucleophilic epoxide ring-opening performed with methanol on a 1,2,3,4-tetrahydroquinoline 3,4-epoxide bearing a related trans ester functionality. The relative stereochemistry of the resulting diol has shown that the the three adjacent substituents are mutually trans disposed. In the crystal structure, centrosymmetric hydrogen-bonded dimers are observed.