2-Hydroxybenzoic acid salt of physostigmine
Abstract
Physostigmine, C15H22N3O2, is the major alkaloid found in the seeds of Calabar beans. It was the first anticholinesterase used in the treatment of Alzheimer's disease and is still used in the treatment of glaucoma. The structure of its 2-hydroxybenzoate salt, viz. 5-carbamoyloxy-1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-1-ium benzoate, C15H22N3O2+·C7H5O3−, is reported.