Volume 50, Issue 3 pp. 332-334
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A novel platinum reagent [chloro(2,2':6',2''-terpyridine)platinum(II) chloride] for use in heavy-atom derivatization of protein crystals

Abstract

A platinum chromophore, chloro(2,2′:6′,2′′-terpyridine)platinum(II) chloride, previously used in labelling active-site histidines of serine proteases, proves to be a useful reagent in heavy-atom derivatization of protein crystals for X-ray crystallographic phase determination.

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