Volume 61, Issue 6 pp. 720-723

The incorporation of large impurities into virus crystals

Yu. G. Kuznetsov

Yu. G. Kuznetsov

Molecular Biology and Biochemistry, University of California, Irvine, 560 Steinhaus Hall, Irvine, CA 92697-3900, USA

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Debora L. Makino

Debora L. Makino

Molecular Biology and Biochemistry, University of California, Irvine, 560 Steinhaus Hall, Irvine, CA 92697-3900, USA

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Alexander J. Malkin

Alexander J. Malkin

Molecular Biology and Biochemistry, University of California, Irvine, 560 Steinhaus Hall, Irvine, CA 92697-3900, USA

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Alexander McPherson

Alexander McPherson

Molecular Biology and Biochemistry, University of California, Irvine, 560 Steinhaus Hall, Irvine, CA 92697-3900, USA

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First published: 16 June 2005
Citations: 1

Abstract

Virus crystals can incorporate a wide range of unusual impurities, not possible for conventional crystals, or even most protein crystals because of the large size of their constituent particles. These impurities include anomalous virions, satellite viruses and biological fibers. Examples of several of these unusual impurities are presented here, along with some of the consequences for the crystal lattices. The high solvent content, the forgiving character of the lattice and the plasticity of the virions allow these incorporations to be possible.

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