Invited Review
Chromosome Aberrations and Gene Mutations in Patients With Esophageal Atresia
Damian Bednarczyk,
Maria M. Sasiadek,
Robert Smigiel,
Damian Bednarczyk
Department of Genetics, Wroclaw Medical University, Wroclaw, Poland
Search for more papers by this authorMaria M. Sasiadek
Department of Genetics, Wroclaw Medical University, Wroclaw, Poland
Search for more papers by this authorCorresponding Author
Robert Smigiel
Department of Genetics, Wroclaw Medical University, Wroclaw, Poland
Address correspondence and reprint requests to Robert Smigiel, MD, PhD, Department of Genetics, Wroclaw Medical University, Marcinkowskiego 1, 50-368 Wroclaw, Poland (e-mail: [email protected]).Search for more papers by this authorDamian Bednarczyk,
Maria M. Sasiadek,
Robert Smigiel,
Damian Bednarczyk
Department of Genetics, Wroclaw Medical University, Wroclaw, Poland
Search for more papers by this authorMaria M. Sasiadek
Department of Genetics, Wroclaw Medical University, Wroclaw, Poland
Search for more papers by this authorCorresponding Author
Robert Smigiel
Department of Genetics, Wroclaw Medical University, Wroclaw, Poland
Address correspondence and reprint requests to Robert Smigiel, MD, PhD, Department of Genetics, Wroclaw Medical University, Marcinkowskiego 1, 50-368 Wroclaw, Poland (e-mail: [email protected]).Search for more papers by this authorSupplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Website (www.jpgn.org).
The authors report no conflicts of interest.
ABSTRACT
Esophageal atresia (EA) is one of the most frequent congenital malformations of the gastrointestinal tract. Many genetic alterations in patients with EA have been described in the literature. It is thought that the etiology of EA is heterogeneous. This review of the literature provides detailed information about chromosomal aberrations, gene mutations, and clinical features of neonates with EA, and serves as an excellent source to compare newly diagnosed patients with those described in the literature.
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