Microcystic variant of localized malignant mesothelioma accompanying an adenomatoid tumor-like lesion
Hajime Umezu
Department of Surgical Pathology, Niigata University Hospital, Japan
Search for more papers by this authorKazuhisa Kuwata
Second Department of Pathology, Niigata University School of Medicine, Niigata City, Japan
Search for more papers by this authorYusuke Ebe
Second Department of Pathology, Niigata University School of Medicine, Niigata City, Japan
Search for more papers by this authorTakashi Yamamoto
Second Department of Pathology, Niigata University School of Medicine, Niigata City, Japan
Search for more papers by this authorMakoto Naito
Second Department of Pathology, Niigata University School of Medicine, Niigata City, Japan
Search for more papers by this authorYasushi Yamato
Second Department of Surgery, Niigata University School of Medicine, Niigata City, Japan and
Search for more papers by this authorTakaaki Ishiyama
Second Department of Surgery, Niigata University School of Medicine, Niigata City, Japan and
Search for more papers by this authorMasanori Tsuchida
Second Department of Surgery, Niigata University School of Medicine, Niigata City, Japan and
Search for more papers by this authorMina Okuizumi
Department of Radiology, Niigata University School of Medicine, Niigata City, Japan
Search for more papers by this authorHiroshi Ishikawa
Department of Radiology, Niigata University School of Medicine, Niigata City, Japan
Search for more papers by this authorNaoya Koizumi
Department of Radiology, Niigata University School of Medicine, Niigata City, Japan
Search for more papers by this authorHajime Umezu
Department of Surgical Pathology, Niigata University Hospital, Japan
Search for more papers by this authorKazuhisa Kuwata
Second Department of Pathology, Niigata University School of Medicine, Niigata City, Japan
Search for more papers by this authorYusuke Ebe
Second Department of Pathology, Niigata University School of Medicine, Niigata City, Japan
Search for more papers by this authorTakashi Yamamoto
Second Department of Pathology, Niigata University School of Medicine, Niigata City, Japan
Search for more papers by this authorMakoto Naito
Second Department of Pathology, Niigata University School of Medicine, Niigata City, Japan
Search for more papers by this authorYasushi Yamato
Second Department of Surgery, Niigata University School of Medicine, Niigata City, Japan and
Search for more papers by this authorTakaaki Ishiyama
Second Department of Surgery, Niigata University School of Medicine, Niigata City, Japan and
Search for more papers by this authorMasanori Tsuchida
Second Department of Surgery, Niigata University School of Medicine, Niigata City, Japan and
Search for more papers by this authorMina Okuizumi
Department of Radiology, Niigata University School of Medicine, Niigata City, Japan
Search for more papers by this authorHiroshi Ishikawa
Department of Radiology, Niigata University School of Medicine, Niigata City, Japan
Search for more papers by this authorNaoya Koizumi
Department of Radiology, Niigata University School of Medicine, Niigata City, Japan
Search for more papers by this authorAbstract
The case of a 70-year-old man with a hitherto undescribed pleural mesothelioma is reported. The tumor was localized in the left lung apex and had invaded the parietal pleura. Histologically, the tumor was characterized by a proliferation of epithelioid cells and the formation of microcysts. The tumor cells were positive for calretinin and vimentin, and possessed abundant microvilli, indicating a mesothelial cell origin for the tumor. A high Ki-67 index and mitotic index, and the recurrence of the tumor after surgery, indicated malignancy. Based on the evidence, we propose that the tumor is a microcystic variant of a localized malignant mesothelioma.
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