Volume 49, Issue 8 pp. 759-762

Heterotopic pancreatic tissue associated with intra- and extrahepatic choledochal cysts

Koyu Suzuki

Koyu Suzuki

Departments of Pathology and

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Toshikazu Uchida

Toshikazu Uchida

Department of Pathology, Nihon University School of Medicine, Tokyo and

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Hisashi Nakayama

Hisashi Nakayama

Surgery, Nihon University Nerimahikarigaoka Hospital,

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Wakato Ugajin

Wakato Ugajin

Surgery, Nihon University Nerimahikarigaoka Hospital,

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Yoshimi Inaniwa

Yoshimi Inaniwa

Departments of Pathology and

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Masahiko Sugitani

Masahiko Sugitani

Department of Pathology, Nihon University School of Medicine, Tokyo and

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Yoshiomi Mori

Yoshiomi Mori

Department of Pathology, Dokkyo Medical School, Saitama, Japan

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First published: 04 January 2002
Citations: 15
Correspondence: KoyuSuzuki MD, Department of Pathology, Nihon University Nerimahikarigaoka Hospital, 2-11-1, Hikarigaoka Nerima-ku, Tokyo 179-0072, Japan

Abstract

A case report of heterotopic pancreas in intra- and extrahepatic biliary tracts in a 36-year-old female who suffered from intra- and extrahepatic choledochal cysts with an anomalous pancreatobiliary duct system. Histologic examination of the resected specimen showed pancreatic tissues located along the wall of the biliary tract with choledochal cysts. The pancreatic tissue consisted of acinar cells and duct elements without Langerhans’ islets; the acinar cells were positive immunohistochemically for α-amylase and negative for endocrine hormones. Ultrastructural study revealed zymogen granules in the acinar cells. In the present case the heterotopic exocrine pancreatic tissue seems to be etiologically related to choledochal cysts as well as to the anomalous arrangement of the pancreatobiliary duct.

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