Volume 27, Issue 1 pp. 53-54

A novel polymorphism in the human interleukin-13 (IL-13) promoter

G. J. Laundy

Corresponding Author

G. J. Laundy

G. J. Laundy, University of Bristol Division of Transplantation Sciences, Southmead Hospital, Westbury-on-Trym, Bristol BS10 5NB, UK.Search for more papers by this author
C. F. Spink

C. F. Spink

Division of Transplantation Sciences, University of Bristol, Bristol, UK, and

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L. J. Keen

L. J. Keen

Division of Transplantation Sciences, University of Bristol, Bristol, UK, and

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N. A. P. Wood

N. A. P. Wood

Department of Pathology and Microbiology, University of Bristol, Bristol, UK.

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J. L. Bidwell

J. L. Bidwell

Department of Pathology and Microbiology, University of Bristol, Bristol, UK.

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First published: 25 December 2001
Citations: 9

Abstract

Using PCR–SSCP and automated nucleotide sequencing we have identified a novel single nucleotide C → T polymorphism in the human IL-13 promoter, at position —1055 relative to the transcription start site. Allele frequency analysis in a population of normal cord blood donors indicated frequencies of 0.833 (C) and 0.167 (T).

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