A novel polymorphism in the human interleukin-13 (IL-13) promoter
Abstract
Using PCR–SSCP and automated nucleotide sequencing we have identified a novel single nucleotide C → T polymorphism in the human IL-13 promoter, at position —1055 relative to the transcription start site. Allele frequency analysis in a population of normal cord blood donors indicated frequencies of 0.833 (C) and 0.167 (T).