Volume 24, Issue 3 pp. 353-358
Article

Radical Resection of Periampullary Tumors in the Elderly: Evaluation of Long-term Results

Oliver F. Bathe

Oliver F. Bathe

Department of Surgery, Division of Surgical Oncology, Sylvester Comprehensive Cancer Center, University of Miami, 1475 NW 12th Avenue, Suite 3550, Miami, Florida 33136, USA

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David Levi

David Levi

Department of Surgery, Division of Surgical Oncology, Sylvester Comprehensive Cancer Center, University of Miami, 1475 NW 12th Avenue, Suite 3550, Miami, Florida 33136, USA

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Humberto Caldera

Humberto Caldera

Department of Medicine, University of Miami, 1475 NW 12th Avenue, Suite 3550, Miami, Florida, 33136 USA

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Dido Franceschi

Dido Franceschi

Department of Surgery, Division of Surgical Oncology, Sylvester Comprehensive Cancer Center, University of Miami, 1475 NW 12th Avenue, Suite 3550, Miami, Florida 33136, USA

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Luis Raez

Luis Raez

Department of Medicine, University of Miami, 1475 NW 12th Avenue, Suite 3550, Miami, Florida, 33136 USA

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Ajay Patel

Ajay Patel

Department of Surgery, Division of Surgical Oncology, Sylvester Comprehensive Cancer Center, University of Miami, 1475 NW 12th Avenue, Suite 3550, Miami, Florida 33136, USA

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William A. Raub Jr.

William A. Raub Jr.

Department of Radiation Oncology, University of Miami, 1475 NW 12th Avenue, Suite 3550, Miami, Florida, 33136 USA

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Pasquale Benedetto

Pasquale Benedetto

Department of Medicine, University of Miami, 1475 NW 12th Avenue, Suite 3550, Miami, Florida, 33136 USA

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Rajender Reddy

Rajender Reddy

Department of Medicine, University of Miami, 1475 NW 12th Avenue, Suite 3550, Miami, Florida, 33136 USA

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Duane Hutson

Duane Hutson

Department of Surgery, Division of Surgical Oncology, Sylvester Comprehensive Cancer Center, University of Miami, 1475 NW 12th Avenue, Suite 3550, Miami, Florida 33136, USA

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Danny Sleeman

Danny Sleeman

Department of Surgery, Division of Surgical Oncology, Sylvester Comprehensive Cancer Center, University of Miami, 1475 NW 12th Avenue, Suite 3550, Miami, Florida 33136, USA

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Alan S. Livingstone

Alan S. Livingstone

Department of Surgery, Division of Surgical Oncology, Sylvester Comprehensive Cancer Center, University of Miami, 1475 NW 12th Avenue, Suite 3550, Miami, Florida 33136, USA

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Joe U. Levi

Joe U. Levi

Department of Surgery, Division of Surgical Oncology, Sylvester Comprehensive Cancer Center, University of Miami, 1475 NW 12th Avenue, Suite 3550, Miami, Florida 33136, USA

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First published: 14 February 2014
Citations: 55

Abstract

Increasingly, patients of advanced age are coming for evaluation of periampullary tumors. Although several studies have demonstrated the safety of resecting periampullary tumors in older patients, few long-term survival data have been reported. Between 1983 and 1992 various periampullary masses were resected in 70 patients over age 65 (range 65–87 years). Total pancreatectomy was performed in 11 patients, and 59 patients underwent pancreaticoduodenectomy. The mean duration of hospitalization was 17 ± 15 days. Major complications occurred in 27 patients (39%), and operative mortality rate was 8.5%. Overall median survival was 24 months; and 5-year survival was 25%. Perioperative outcome was compared in patients aged 65 to 74 years and in patients ≥75 years old. The older age group required longer periods in the surgical intensive care unit postoperatively, but the long-term survival was similar in the two age groups. Radical resection with the intent to cure periampullary tumors is safe in selected patients of advanced age, and long-term survival is in the range of expected survival for younger patients with the same tumors.

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