Article
Definition of Barrett’s Esophagus Dysplasia: Are We Speaking the Same Language?
Massimo Rugge,
Marco Pizzi,
Carlo Castoro,
Corresponding Author
Massimo Rugge
- [email protected]
- +39 049 8272266
Department of Medicine-DIMED, Surgical Pathology and Cytopathology Unit, University of Padova, via A. Gabelli, 61, 35121 Padova, Italy
Department of Surgery, Istituto Oncologico Veneto – IOV, Padova, Italy
Tel.: +39 049 8272266, [email protected]Search for more papers by this authorMarco Pizzi
Department of Medicine-DIMED, Surgical Pathology and Cytopathology Unit, University of Padova, via A. Gabelli, 61, 35121 Padova, Italy
Search for more papers by this authorCarlo Castoro
Department of Surgery, Istituto Oncologico Veneto – IOV, Padova, Italy
Search for more papers by this authorMassimo Rugge,
Marco Pizzi,
Carlo Castoro,
Corresponding Author
Massimo Rugge
- [email protected]
- +39 049 8272266
Department of Medicine-DIMED, Surgical Pathology and Cytopathology Unit, University of Padova, via A. Gabelli, 61, 35121 Padova, Italy
Department of Surgery, Istituto Oncologico Veneto – IOV, Padova, Italy
Tel.: +39 049 8272266, [email protected]Search for more papers by this authorMarco Pizzi
Department of Medicine-DIMED, Surgical Pathology and Cytopathology Unit, University of Padova, via A. Gabelli, 61, 35121 Padova, Italy
Search for more papers by this authorCarlo Castoro
Department of Surgery, Istituto Oncologico Veneto – IOV, Padova, Italy
Search for more papers by this authorAbstract
The definition of Barrett’s esophagus (BE) is still a matter of debate. The diagnostic criteria adopted around the world for both BE and BE-related pre-cancerous lesions are inconsistent, particularly between Eastern and Western pathologists. From a clinical perspective, these different clinico-biological approaches may affect how the literature is interpreted, with detrimental effects on the clinical management of patients. The present review focuses on the major discrepancies in the field, covering both the non-neoplastic and the pre-cancerous lesions associated with Barrett’s disease.
References
- 1DescartesR Discourse on method and meditations on first philosophy (1998) IndianapolisHackett Publishing Company
- 2BarrettNR Chronic peptic ulcer of the oesophagus and “oesophagitis”. Br J Surg (1950) 38: 175–18210.1002/bjs.1800381500514791960
- 3RiddellRH, OdzeRD Definition of Barrett’s esophagus: time for a rethinkߝis intestinal metaplasia dead?. Am J Gastroenterol (2009) 104(10): 2588–259410.1038/ajg.2009.39019623166
- 4de JongePJ, van BlankensteinM, GradyWM et al. Barrett’s oesophagus: epidemiology, cancer risk and implications for management. Gut (2014) 63(1): 191–20210.1136/gutjnl-2013-30549024092861
- 5TakuboK, AraiT, SawabeM et al. Structures of the normal esophagus and Barrett’s esophagus. Esophagus (2003) 1: 37–4710.1007/s10388-003-0004-y
10.1007/s10388-003-0004-y Google Scholar
- 6Hvid-JensenF, PedersenL, DrewesAM et al. Incidence of adenocarcinoma among patients with Barrett’s esophagus. N Engl J Med (2011) 365: 1375–138310.1056/NEJMoa110304221995385
- 7RuggeM, CapelleLG, CappellessoR et al. Precancerous lesions in the stomach: from biology to clinical patient management. Best Pract Res Clin Gastroenterol (2013) 27(2): 205–22310.1016/j.bpg.2012.12.00723809241
- 8 Japan Esophageal SocietyJapanese classification of esophageal cancer, tenth edition: parts II and III. Esophagus (2009) 6: 71–9410.1007/s10388-009-0193-0
- 9FitzgeraldRC, di PietroM, RagunathK et al. British Society of Gastroenterology guidelines on the diagnosis and management of Barrett’s oesophagus. Gut (2014) 63(1): 7–4210.1136/gutjnl-2013-30537224165758
- 10JassJR Discrepancies between East and West. Cancer (2000) 88(5): 969–97010.1002/(SICI)1097-0142(20000301)88:5<969::AID-CNCR2>3.0.CO;2-D10699881
10.1002/(SICI)1097-0142(20000301)88:5<969::AID-CNCR2>3.0.CO;2-D CAS PubMed Web of Science® Google Scholar
- 11MuellerJ, WernerM, StolteM Barrett’s esophagus: histopathologic definitions and diagnostic criteria. World J Surg (2004) 28(2): 148–15410.1007/s00268-003-7050-414727064
- 12PaullA, TrierJS, DaltonMD et al. The histologic spectrum of Barrett’s esophagus. N Engl J Med (1976) 295: 476–48010.1056/NEJM197608262950904940579
- 13FioccaR, MastracciL, MilioneM et al. Microscopic esophagitis and Barrett’s esophagus: the histology report. Dig Liver Dis (2011) 43(Suppl 4): S319–S33010.1016/S1590-8658(11)60588-421459338
- 14TakuboK, ViethM, AidaJ et al. Differences in the definitions used for esophageal and gastric diseases in different countries: endoscopic definition of the esophagogastric junction, the precursor of Barrett’s adenocarcinoma, the definition of Barrett’s esophagus, and histologic criteria for mucosal adenocarcinoma or high-grade dysplasia. Digestion (2009) 80(4): 248–25710.1159/00023592319828957
- 15SharmaP, DentJ, ArmstrongD et al. The development and validation of an endoscopic grading system for Barrett’s esophagus: the Prague C & M criteria. Gastroenterology (2006) 131(5): 1392–139910.1053/j.gastro.2006.08.03217101315
- 16SpechlerSJ, SharmaP, SouzaRF et al. American Gastroenterological Association technical review on the management of Barrett’s esophagus. Gastroenterology (2011) 140: e18–e5210.1053/j.gastro.2011.01.03121376939
- 17AmanoY, IshimuraN, FurutaK et al. Which landmark results in a more consistent diagnosis of Barrett’s esophagus, the gastric folds or the palisade vessels?. Gastrointest Endosc (2006) 64: 206–21110.1016/j.gie.2006.04.02916860070
- 18RuggeM, FassanM, BattagliaG et al. Intestinal or gastric? The unsolved dilemma of Barrett’s metaplasia. Hum Pathol (2009) 40(8): 1206–120710.1016/j.humpath.2009.03.02219616698
- 19SmithRR, HamiltonSR, BoitnottJK et al. The spectrum of carcinoma arising in Barrett’s esophagus. A clinicopathologic study of 26 patients. Am J Surg Pathol (1984) 8: 563–57310.1097/00000478-198408000-000016465417
- 20BhatS, ColemanHG, YousefF et al. Risk of malignant progression in Barrett’s esophagus patients: results from a large population-based study. J Natl Cancer Inst (2011) 103: 1049–105710.1093/jnci/djr20321680910
- 21SpechlerSJ, SharmaP, SouzaRF et al. American Gastroenterological Association medical position statement on the management of Barrett’s esophagus. Gastroenterology (2011) 140(3): 1084–109110.1053/j.gastro.2011.01.03121376940
- 22VakilN, van ZantenSV, KahrilasP et al. The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus. Am J Gastroenterol (2006) 101(8): 1900–192010.1111/j.1572-0241.2006.00630.x16928254
- 23JankowskiJA, HarrisonRF, PerryI et al. Barrett’s metaplasia. Lancet (2000) 356(9247): 2079–208510.1016/S0140-6736(00)03411-511145505
- 24KeltyCJ, GoughMD, Van WykQ et al. Barrett’s oesophagus: intestinal metaplasia is not essential for cancer risk. Scand J Gastroenterol (2007) 42(11): 1271–127410.1080/0036552070142073517852872
- 25TakuboK, AidaJ, NaomotoY et al. Cardiac rather than intestinal-type background in endoscopic resection specimens of minute Barrett adenocarcinoma. Hum Pathol (2009) 40: 65–7410.1016/j.humpath.2008.06.00818755496
- 26 Japan Esophageal SocietyJapanese classification of esophageal cancer, tenth edition: part I. Esophagus (2009) 6: 1–2510.1007/s10388-009-0169-0
- 27HahnHP, BlountPL, AyubK et al. Intestinal differentiation in metaplastic, nongoblet columnar epithelium in the esophagus. Am J Surg Pathol (2009) 33(7): 1006–101510.1097/PAS.0b013e31819f57e919363439
- 28FassanM, VoliniaS, PalatiniJ et al. MicroRNA expression profiling in the histological subtypes of Barrett’s metaplasia. Clin Transl Gastroenterol (2013) 4: e3410.1038/ctg.2013.523677165
- 29OryuM, MoriH, KobaraH et al. Differences in the characteristics of Barrett’s esophagus and Barrett’s adenocarcinoma between the United States and Japan. ISRN Gastroenterol (2013) 2013: 84069010.1155/2013/84069023606979
- 30OdzeRD, RiddellRH, BosmanFT et al. et al. FT Bosman, F Carneiro, RH Hruban et al. et al. Premalignant lesions of the digestive system. WHO classification of tumours of the digestive system (2010) LyonIARC 10–12
- 31SchlemperRJ, ItabashiM, KatoY et al. Differences in diagnostic criteria for gastric carcinoma between Japanese and Western pathologists. Lancet (1997) 349(9067): 1725–172910.1016/S0140-6736(96)12249-29193382
- 32TakuboK, AraiT, IshiguroS M Imamura Patient presentation and pathologic diagnosis of superficial carcinoma of the esophagus: high-grade dysplasia and mucosal carcinoma from the Japanese standpoint. Superficial esophageal neoplasm: pathology, diagnosis, and therapy (2002) TokyoSpringer 141–14710.1007/978-4-431-67873-1_19
10.1007/978-4-431-67873-1_19 Google Scholar
- 33RuggeM, CorreaP, DixonMF et al. Gastric dysplasia: the Padova international classification. Am J Surg Pathol (2000) 24(2): 167–17610.1097/00000478-200002000-0000110680883
- 34FassanM, PizziM, FarinatiF et al. Lesions indefinite for intraepithelial neoplasia and OLGA staging for gastric atrophy. Am J Clin Pathol (2012) 137: 727–73210.1309/AJCPEU41HTGXSJDQ22523210
- 35 Japanese Gastric Cancer AssociationJapanese classification of esophageal cancer, tenth edition: part I. Gastric Cancer (2011) 14: 101–11210.1007/s10120-011-0041-5
- 36SchlemperRJ, RiddellRH, KatoY et al. The Vienna classification of gastrointestinal epithelial neoplasia. Gut (2000) 47: 251–25510.1136/gut.47.2.25110896917
- 37DixonMF Gastrointestinal epithelial neoplasia: Vienna revisited. Gut (2002) 51(1): 130–13110.1136/gut.51.1.13012077106
- 38DobbinsW The intestinal mucosal lymphatic in man. A light and electron microscopic study. Gastroenterol (1966) 51(6): 994–1003
- 39AkashiY, NoguchiT, NagaiK et al. Cytoarchitecture of the lamina muscularis mucosae and distribution of the lymphatic vessels in the human stomach. Med Mol Morphol (2011) 44(1): 39–4510.1007/s00795-010-0503-621424936
- 40FlejouJF, OdzeRD, MontgomeryE et al. et al. FT Bosman, F Carneiro, RH Hruban et al. et al. Adenocarcinoma of the oesophagus. WHO classification of tumours of the digestive system (2010) LyonIARC p27–p28
- 41Fassan M, Baffa R, Kiss A et al (2013) MicroRNA dysregulation in esophageal neoplasia: the biological rationale for novel therapeutic options. Curr Pharm Des 19(7): 1236–1241
- 42Pizzi M, Fassan M, Realdon S et al (2012) Anterior gradient 2 profiling in Barrett columnar epithelia and adenocarcinoma. Hum Pathol 43(11): 1839–1844
