In this paper we study the global boundedness of solutions to the quasilinear chemotaxis-Stokes system with nonlinear production
() subject to no-flux/no-flux/Dirichlet boundary conditions in a smoothly bounded domain
with
, where
,
, and
generalize the prototypes
and
for all
with
and
. It is shown that if
for
, or
for
, then for any reasonably regular initial datum, the corresponding initial-boundary value problem of (
) possesses a unique globally bounded classical solution. Compared to the global boundedness condition
for
in the relevant fluid-free system [J. Differ. Equ. 268 6729–6777 (2020)], the present result indicates that the slow fluid motion described by the Stokes equation might possibly be adverse to the global solvability in the case that
with
. What is more, this paper provides for the quasilinear problems with general signal production a universal approach capable of deriving the boundedness of solutions in the optimal range of parameters.