Cancer Therapy: A Glucose/Oxygen-Exhausting Nanoreactor for Starvation- and Hypoxia-Activated Sustainable and Cascade Chemo-Chemodynamic Therapy (Small 31/2020)
Graphical Abstract
Sustainable and cascade anticancer strategies have attracted great attention due to their excellent therapeutic performance. In article number 2000897, Fu-Gen Wu and co-workers present a self-amplified nanoreactor for cancer treatment. The nanoreactor can convert oxygen into HO• for chemodynamic therapy, consume glucose for starvation therapy, and provide a hypoxic environment for hypoxia-activated chemotherapy.