Volume 10, Issue 19 pp. 3912-3917
Communication

Paper-Based DNA Detection Using Lanthanide-Doped LiYF4 Upconversion Nanocrystals As Bioprobe

Qiang Ju

Qiang Ju

Chemical Sensors Group, Department of Chemical and Physical Sciences, University of Toronto, 3359 Mississauga Road, Mississauga Ontario, Canada, L5L 1C6

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Uvaraj Uddayasankar

Uvaraj Uddayasankar

Chemical Sensors Group, Department of Chemical and Physical Sciences, University of Toronto, 3359 Mississauga Road, Mississauga Ontario, Canada, L5L 1C6

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Ulrich Krull

Corresponding Author

Ulrich Krull

Chemical Sensors Group, Department of Chemical and Physical Sciences, University of Toronto, 3359 Mississauga Road, Mississauga Ontario, Canada, L5L 1C6

E-mail: [email protected]Search for more papers by this author
First published: 16 May 2014
Citations: 43

Graphical Abstract

A novel sensitive DNA bioassay using lanthanide-doped LiYF4 upconversion nanocrystals as luminescent marker and oligonucleotide hybridization as the selective reaction is developed in a paper-based platform, providing a detection limit of 3.6 fmol.

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