REVIEW
The genus Calea L.: A review on traditional uses, phytochemistry, and biological activities
Tamires Cardoso Lima,
Rafaela de Jesus Souza,
Francilene Amaral da Silva,
Maique Weber Biavatti,
Tamires Cardoso Lima
Departamento de Farmácia, CCBS, Universidade Federal de Sergipe (UFS), São Cristóvão, SE, Brazil
Search for more papers by this authorRafaela de Jesus Souza
Departamento de Ciências Farmacêuticas, CCS, Universidade Federal de Santa Catarina (UFSC), Florianópolis, SC, Brazil
Search for more papers by this authorFrancilene Amaral da Silva
Departamento de Farmácia, CCBS, Universidade Federal de Sergipe (UFS), São Cristóvão, SE, Brazil
Search for more papers by this authorCorresponding Author
Maique Weber Biavatti
Departamento de Ciências Farmacêuticas, CCS, Universidade Federal de Santa Catarina (UFSC), Florianópolis, SC, Brazil
Correspondence
Maique Weber Biavatti, Departamento de Ciências Farmacêuticas, CCS, Universidade Federal de Santa Catarina (UFSC), Florianópolis – SC, Brazil.
Email: [email protected]
Search for more papers by this authorTamires Cardoso Lima,
Rafaela de Jesus Souza,
Francilene Amaral da Silva,
Maique Weber Biavatti,
Tamires Cardoso Lima
Departamento de Farmácia, CCBS, Universidade Federal de Sergipe (UFS), São Cristóvão, SE, Brazil
Search for more papers by this authorRafaela de Jesus Souza
Departamento de Ciências Farmacêuticas, CCS, Universidade Federal de Santa Catarina (UFSC), Florianópolis, SC, Brazil
Search for more papers by this authorFrancilene Amaral da Silva
Departamento de Farmácia, CCBS, Universidade Federal de Sergipe (UFS), São Cristóvão, SE, Brazil
Search for more papers by this authorCorresponding Author
Maique Weber Biavatti
Departamento de Ciências Farmacêuticas, CCS, Universidade Federal de Santa Catarina (UFSC), Florianópolis, SC, Brazil
Correspondence
Maique Weber Biavatti, Departamento de Ciências Farmacêuticas, CCS, Universidade Federal de Santa Catarina (UFSC), Florianópolis – SC, Brazil.
Email: [email protected]
Search for more papers by this authorAbstract
Calea L. is a genus of shrubs and perennial herbs belonging to Asteraceae family. It is a very well-known genus, consisting of approximately 125 neotropical species. Calea genus is a rich source of phytochemicals, and some of its species have been used in folk medicine to treat several health problems such as diabetes, arterial hypertension, respiratory and gastrointestinal disorders, gastric ulcers, and inflammation. Many studies have demonstrated the pharmacological potential of this genus, including antinociceptive, antihypertensive, antidiarrheal, antimicrobial, anti-inflammatory, antidiabetic, antiproliferative, and cytotoxic activities. Moreover, bioactive constituents related to these properties are mainly sesquiterpene lactones and phenolic derivatives. In this review, we compiled the literature data up to December 2016, furnishing a comprehensive survey about medicinal uses, chemistry, and biological activities from Calea species. Bibliographic search was performed in several search engines using “Calea” as search keyword. Further, a manual literature search of references found in the selected studies was also conducted. There was no initial time limit.
CONFLICT OF INTEREST
The authors declare no conflict of interest.
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