Miniaturised eight-channel impedance spectroscopy unit as sensor platform for biosensor applications
Corresponding Author
Jeroen Broeders
Institute for Materials Research, Hasselt University, Wetenschapspark 1, 3590 Diepenbeek, Belgium
Xios University College, Agoralaan Gebouw H, 3590 Diepenbeek, Belgium
Phone: +32-011-26-88-35, Fax: +32-011-26-88-99Search for more papers by this authorStijn Duchateau
Xios University College, Agoralaan Gebouw H, 3590 Diepenbeek, Belgium
Search for more papers by this authorBart Van Grinsven
Institute for Materials Research, Hasselt University, Wetenschapspark 1, 3590 Diepenbeek, Belgium
Search for more papers by this authorWouter Vanaken
Xios University College, Agoralaan Gebouw H, 3590 Diepenbeek, Belgium
Search for more papers by this authorMarloes Peeters
Institute for Materials Research, Hasselt University, Wetenschapspark 1, 3590 Diepenbeek, Belgium
Search for more papers by this authorThomas Cleij
Xios University College, Agoralaan Gebouw H, 3590 Diepenbeek, Belgium
Search for more papers by this authorRonald Thoelen
Xios University College, Agoralaan Gebouw H, 3590 Diepenbeek, Belgium
Search for more papers by this authorPatrick Wagner
Institute for Materials Research, Hasselt University, Wetenschapspark 1, 3590 Diepenbeek, Belgium
IMEC, Devision IMOMEC, Wetenschapspark 1, 3590 Diepenbeek, Belgium
Search for more papers by this authorWard De Ceuninck
Institute for Materials Research, Hasselt University, Wetenschapspark 1, 3590 Diepenbeek, Belgium
IMEC, Devision IMOMEC, Wetenschapspark 1, 3590 Diepenbeek, Belgium
Search for more papers by this authorCorresponding Author
Jeroen Broeders
Institute for Materials Research, Hasselt University, Wetenschapspark 1, 3590 Diepenbeek, Belgium
Xios University College, Agoralaan Gebouw H, 3590 Diepenbeek, Belgium
Phone: +32-011-26-88-35, Fax: +32-011-26-88-99Search for more papers by this authorStijn Duchateau
Xios University College, Agoralaan Gebouw H, 3590 Diepenbeek, Belgium
Search for more papers by this authorBart Van Grinsven
Institute for Materials Research, Hasselt University, Wetenschapspark 1, 3590 Diepenbeek, Belgium
Search for more papers by this authorWouter Vanaken
Xios University College, Agoralaan Gebouw H, 3590 Diepenbeek, Belgium
Search for more papers by this authorMarloes Peeters
Institute for Materials Research, Hasselt University, Wetenschapspark 1, 3590 Diepenbeek, Belgium
Search for more papers by this authorThomas Cleij
Xios University College, Agoralaan Gebouw H, 3590 Diepenbeek, Belgium
Search for more papers by this authorRonald Thoelen
Xios University College, Agoralaan Gebouw H, 3590 Diepenbeek, Belgium
Search for more papers by this authorPatrick Wagner
Institute for Materials Research, Hasselt University, Wetenschapspark 1, 3590 Diepenbeek, Belgium
IMEC, Devision IMOMEC, Wetenschapspark 1, 3590 Diepenbeek, Belgium
Search for more papers by this authorWard De Ceuninck
Institute for Materials Research, Hasselt University, Wetenschapspark 1, 3590 Diepenbeek, Belgium
IMEC, Devision IMOMEC, Wetenschapspark 1, 3590 Diepenbeek, Belgium
Search for more papers by this authorAbstract
A miniaturised, low cost impedance analyser is developed to ease the use of impedance spectroscopy in biological setups. This could form the first step towards fully standalone, hand-held biosensor applications. The system is capable of performing quasi-simultaneous time resolved impedance measurements on eight different channels in a frequency range of 10 Hz–100 kHz. The unit is accurate in a broad impedance range and is able to perform stable measurements over intervals of several days. The system is characterised by passive components, a temperature controlled wet cell based impedance setup and a biomimetic molecularly imprinted polymer (MIP) based histamine sensor. The test results all indicate accurate and stable functioning of the unit, making it suitable for bioanalytical applications.
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