Pulmonary diffusing capacity measured by NO/CO transfer in Tunisian boys
Corresponding Author
Rim Dridi PhD
Research Unit 17JS01 (Sport, Performance, Health and Society), High Institute of Sport and Physical Education of Ksar Said, Tunisia
Correspondence Rim Dridi, Research Unit 17JS01 (Sport, Performance, Health and Society), High Institute of Sport and Physical Education of Ksar Said. 2000, Tunis, Tunisia.
Email: [email protected]
Hassane Zouhal, PhD, Université de Rennes, M2S (Laboratoire Mouvement, Sport, Santé) - EA 1274, F-35000 Rennes, France.
Email: [email protected]
Search for more papers by this authorNadia Dridi MS
Research Unit 17JS01 (Sport, Performance, Health and Society), High Institute of Sport and Physical Education of Ksar Said, Tunisia
Search for more papers by this authorAmira Ben Moussa Zouita PhD
Research Unit 17JS01 (Sport, Performance, Health and Society), High Institute of Sport and Physical Education of Ksar Said, Tunisia
Search for more papers by this authorPaulo T. Muller PhD
Laboratory of Respiratory Pathophysiology (LAFIR), Federal University of Mato Grosso do Sul, Campo Grande, Brazil
Search for more papers by this authorZouhair Tabka MD, PhD
Department of Physiology and Lung Function Testing, Faculty of Medicine of Sousse, Tunisia
Search for more papers by this authorHervé Guénard MD, PhD
Department of Physiology, Victor Segalen University, Bordeaux, France
Search for more papers by this authorIsmail Laher PhD
Department of Anesthesiology, Pharmacology and Therapeutics, Faculty of Medicine, University of British Columbia, Vancouver, Canada
Search for more papers by this authorAnthony C. Hackney PhD
Department of Exercise & Sport Science, University of North Carolina, Chapel Hill, North Carolina
Search for more papers by this authorCorresponding Author
Hassane Zouhal PhD
Université de Rennes, M2S (Laboratoire Mouvement, Sport, Santé), Rennes, France
Correspondence Rim Dridi, Research Unit 17JS01 (Sport, Performance, Health and Society), High Institute of Sport and Physical Education of Ksar Said. 2000, Tunis, Tunisia.
Email: [email protected]
Hassane Zouhal, PhD, Université de Rennes, M2S (Laboratoire Mouvement, Sport, Santé) - EA 1274, F-35000 Rennes, France.
Email: [email protected]
Search for more papers by this authorCorresponding Author
Rim Dridi PhD
Research Unit 17JS01 (Sport, Performance, Health and Society), High Institute of Sport and Physical Education of Ksar Said, Tunisia
Correspondence Rim Dridi, Research Unit 17JS01 (Sport, Performance, Health and Society), High Institute of Sport and Physical Education of Ksar Said. 2000, Tunis, Tunisia.
Email: [email protected]
Hassane Zouhal, PhD, Université de Rennes, M2S (Laboratoire Mouvement, Sport, Santé) - EA 1274, F-35000 Rennes, France.
Email: [email protected]
Search for more papers by this authorNadia Dridi MS
Research Unit 17JS01 (Sport, Performance, Health and Society), High Institute of Sport and Physical Education of Ksar Said, Tunisia
Search for more papers by this authorAmira Ben Moussa Zouita PhD
Research Unit 17JS01 (Sport, Performance, Health and Society), High Institute of Sport and Physical Education of Ksar Said, Tunisia
Search for more papers by this authorPaulo T. Muller PhD
Laboratory of Respiratory Pathophysiology (LAFIR), Federal University of Mato Grosso do Sul, Campo Grande, Brazil
Search for more papers by this authorZouhair Tabka MD, PhD
Department of Physiology and Lung Function Testing, Faculty of Medicine of Sousse, Tunisia
Search for more papers by this authorHervé Guénard MD, PhD
Department of Physiology, Victor Segalen University, Bordeaux, France
Search for more papers by this authorIsmail Laher PhD
Department of Anesthesiology, Pharmacology and Therapeutics, Faculty of Medicine, University of British Columbia, Vancouver, Canada
Search for more papers by this authorAnthony C. Hackney PhD
Department of Exercise & Sport Science, University of North Carolina, Chapel Hill, North Carolina
Search for more papers by this authorCorresponding Author
Hassane Zouhal PhD
Université de Rennes, M2S (Laboratoire Mouvement, Sport, Santé), Rennes, France
Correspondence Rim Dridi, Research Unit 17JS01 (Sport, Performance, Health and Society), High Institute of Sport and Physical Education of Ksar Said. 2000, Tunis, Tunisia.
Email: [email protected]
Hassane Zouhal, PhD, Université de Rennes, M2S (Laboratoire Mouvement, Sport, Santé) - EA 1274, F-35000 Rennes, France.
Email: [email protected]
Search for more papers by this authorAbstract
Background
The diffusing capacity, which measures gas-exchange, uses reference values based on data from American or European studies. There are currently no reference values of pulmonary diffusing capacity (TL) and its components, such as the conductance of the membrane (Dm) and capillary lung volume (Vc) for healthy North African children.
Objectives
We determined the prediction equations—reference values for TL, Dm, Vc and the alveolar volume (VA) in healthy Tunisian boys.
Methods
Values of Vc, Dm, TL, and VA were measured by the NO/CO transfer method, using a single breath maneuver in 118 Tunisian boys (8-14 years old) at rest. We performed linear regression analysis of the pulmonary parameters and independent variables, such as height, weight, and age.
Results
The reference equations for pulmonary diffusing capacity for carbon monoxide (TLCO) was 0.201 × weight (kg) + 8.979; for TLNO was 0.76 × height (cm)-24.383; for Dm was 0.388 × height (cm)- 12.555 and for VA was 0.34 × height (cm)-3.951. Vc increased significantly with weight (P < .05) but not with age (P > .05).
Conclusions
References norms for TLCO and TL for nitric oxide and its components in young Tunisian boys are similar to data from other countries. The prediction equations we developed can be extended to clinical practice in Tunisia and can be considered for use in neighboring North African countries.
CONFLICT OF INTERESTS
The authors declare that there are no conflict of interests.
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