Cover Image, Volume 58, Issue 16

Cationic graft copolymers containing biodegradable segments are promising candidates as gene delivery systems. In the study on page 2168 by Leon Perez and colleagues, the grafting of low-molecular-weight poly(2-(dimethylamino)ethyl methacrylate) to poly(esterco-carbonate) backbones was achieved through two different approaches: grafting to and grafting from. The most versatile strategy for attaining a set of materials with a tailored structure and composition was grafting from, which in turn allowed for highlighting relationships between properties and copolymers' composition. (DOI: 10.1002/pol.20200204)