Editorial
Disproportionality analyses of spontaneous reports
Sean Hennessy PharmD, PhD,
Corresponding Author
Sean Hennessy PharmD, PhD
Assistant Professor of Epidemiology and of Pharmacology, Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, Center for Education and Research in Therapeutics, University of Pennsylvania School of Medicine, 423 Guardian Drive/803 Blockley Hall, Philadelphia, PA 19104-6021, USA
Assistant Professor of Epidemiology and of Pharmacology, Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, Center for Education and Research in Therapeutics, University of Pennsylvania School of Medicine, 423 Guardian Drive/803 Blockley Hall, Philadelphia, PA 19104-6021, USA.Search for more papers by this authorSean Hennessy PharmD, PhD,
Corresponding Author
Sean Hennessy PharmD, PhD
Assistant Professor of Epidemiology and of Pharmacology, Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, Center for Education and Research in Therapeutics, University of Pennsylvania School of Medicine, 423 Guardian Drive/803 Blockley Hall, Philadelphia, PA 19104-6021, USA
Assistant Professor of Epidemiology and of Pharmacology, Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, Center for Education and Research in Therapeutics, University of Pennsylvania School of Medicine, 423 Guardian Drive/803 Blockley Hall, Philadelphia, PA 19104-6021, USA.Search for more papers by this authorNo abstract is available for this article.
REFERENCES
- 1 Evans SJ, Waller PC, Davis S. Use of proportional reporting ratios (PRRs) for signal generation from spontaneous adverse drug reaction reports. Pharmacoepidemiol Drug Safe 2001; 10: 483–486.
- 2 Rothman KJ, Lanes S, Sacks ST. The reporting odds ratio and its advantages over the proportional reporting ratio. Pharmacoepidemiol Drug Safe 2004; 13: 519–523.
- 3 van Puijenbroek EP, Bate A, Leufkens HG, Lindquist M, Orre R, Egberts AC. A comparison of measures of disproportionality for signal detection in spontaneous reporting systems for adverse drug reactions. Pharmacoepidemiol Drug Safe 2002; 11: 3–10.
- 4 Waller P. The reporting odds ratio versus the proportional reporting ratio: deuce. Pharmacoepidemiol Drug Safe 2004; 13: 525–526.
- 5 Moore N, Hall G, Sturkenboom M, Mann R, Lagnaoui R, Begaud B. Biases affecting the proportional reporting ratio (PPR) in spontaneous reports pharmacovigilance databases: the example of sertindole. Pharmacoepidemiol Drug Safe 2003; 12: 271–281.
- 6 Waller P. Dealing with uncertainty in drug safety: lessons for the future from sertindole. Pharmacoepidemiol Drug Safe 2003; 12: 283–287.
- 7 Strom BL. Study designs available for pharmacoepidemiology studies. In Pharmacoepidemiology, 3rd edn, BL Strom (ed.). John Wiley and Sons, Inc.: Chichester, UK, 2000.
- 8 De Bruin ML, van Puijenbroek EP, Egberts AC, Hoes AW, Leufkens HG. Non-sedating antihistamine drugs and cardiac arrhythmias—biased risk estimates from spontaneous reporting systems? Br J Clin Pharmacol 2002; 53: 370–374.
- 9 Zhou W, Pool V, DeStefano F, Iskander JK, Haber P, Chen RT. A possible signal of Bell's palsy after parenteral inactivated influenza vaccines: reports to the vaccine adverse event reporting system (VAERS)—United States, 1991–2001. Pharmacoepidemiol Drug Safe 2004; 13: 505–510.
Citing Literature
