Volume 71, Issue 10 e31222
RESEARCH ARTICLE

Standardizing the evaluation and management of iron deficiency anemia secondary to heavy menstrual bleeding in the emergency department

Josaura Fernandez Sanchez

Josaura Fernandez Sanchez

Department of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA

Texas Children's Cancer and Hematology Center, Houston, Texas, USA

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Luisanna M. Sánchez

Corresponding Author

Luisanna M. Sánchez

Department of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA

Texas Children's Cancer and Hematology Center, Houston, Texas, USA

Correspondence

Luisanna M. Sánchez, Indiana Hemophilia and Thrombosis Center, 8326 Naab Rd, Indianapolis, IN 46260, USA.

Email: [email protected]

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Sarah S. Kappa

Sarah S. Kappa

Department of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA

Texas Children's Cancer and Hematology Center, Houston, Texas, USA

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Cecile L. Karsenty

Cecile L. Karsenty

Department of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA

Texas Children's Cancer and Hematology Center, Houston, Texas, USA

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Madeleine O'Keefe

Madeleine O'Keefe

Department of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA

Texas Children's Cancer and Hematology Center, Houston, Texas, USA

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Meghan Shekar

Meghan Shekar

Department of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA

Texas Children's Cancer and Hematology Center, Houston, Texas, USA

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Leander D. Timothy

Leander D. Timothy

Department of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA

Texas Children's Cancer and Hematology Center, Houston, Texas, USA

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Chelsea B. Vrana

Chelsea B. Vrana

Department of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA

Texas Children's Cancer and Hematology Center, Houston, Texas, USA

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Gladstone Airewele

Gladstone Airewele

Department of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA

Texas Children's Cancer and Hematology Center, Houston, Texas, USA

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YoungNa Lee-Kim

YoungNa Lee-Kim

Department of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA

Texas Children's Cancer and Hematology Center, Houston, Texas, USA

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M. Fatih Okcu

M. Fatih Okcu

Department of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA

Texas Children's Cancer and Hematology Center, Houston, Texas, USA

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Clay T. Cohen

Clay T. Cohen

Department of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA

Texas Children's Cancer and Hematology Center, Houston, Texas, USA

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Jacquelyn M. Powers

Jacquelyn M. Powers

Department of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston, Texas, USA

Texas Children's Cancer and Hematology Center, Houston, Texas, USA

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First published: 25 July 2024

Josaura Fernandez Sanchez and Luisanna M. Sánchez are the co-first authors.

Clay T. Cohen and Jacquelyn M. Powers are the co-senior authors.

Meeting abstract publication: Abstract from poster presentation at ASPHO May 2023, published in 2023 ASPHO Conference Paper and Poster Index. Pediatr Blood Cancer. 70:e30390, pS131.

Abstract

Background

Comprehensive guidelines for the management of iron deficiency anemia (IDA) in adolescents with heavy menstrual bleeding (HMB) presenting to the emergency department (ED) are lacking, leading to variability in care. We aimed to standardize the evaluation and management of these patients through the development and implementation of an evidence-based algorithm using quality improvement methodology.

Methods

Baseline data of the target population identified variability across four key measures of clinical management: therapy choice and administration, laboratory evaluation, hematology service consultation, and patient disposition. Literature review and consensus from pediatric hematology and gynecology providers informed a draft algorithm that was refined in an iterative multidisciplinary process. From December 2022 to July 2023, we aimed to achieve a 25% relative increase in patients to receive optimal management per the algorithm, while using sequential Plan–Do–Study–Act (PDSA) cycles. Process measures focusing on provider documentation and balancing measures, such as ED length of stay, were assessed concurrently.

Results

Forty-nine patients were evaluated during four PDSA cycles. Improvement of ≥40% above baseline regarding recommended therapy administration was achieved across four PDSA cycles. Adherence to recommended therapy choice improved from 57% (baseline) to 100%, minimal laboratory evaluation from 14% to 83%, hematology consultation from 36% to 100%, and appropriate disposition from 71% to 100%. ED length of stay remained stable.

Conclusion

Implementation of a standardized algorithm for management of IDA secondary to HMB in adolescents in the ED increased adherence to evidence-based patient care.

CONFLICT OF INTEREST STATEMENT

The authors declare no conflicts of interest.

DATA AVAILABILITY STATEMENT

The data that support the findings of this study are available from the corresponding author upon reasonable request.

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