Volume 64, Issue 7 e26385

BRIEF REPORT

Successful treatment of mature B-cell lymphoma with rituximab-based chemotherapy in a patient with Bloom syndrome

Wasil Jastaniah,

Corresponding Author

Wasil Jastaniah

[email protected]

College of Medicine, Department of Pediatrics, Umm AlQura University, Makkah, Saudi Arabia

Princess Noorah Oncology Center, King Abdulaziz Medical City, Jeddah, Saudi Arabia

Correspondence

Wasil Jastaniah, College of Medicine, Department of Pediatrics, Umm AlQura University and Princess Noorah Oncology Center, King Abdulaziz Medical City, P.O. Box 9515, Jeddah 21423, Saudi Arabia.

Email: [email protected]

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Wasil Jastaniah,

Corresponding Author

Wasil Jastaniah

[email protected]

College of Medicine, Department of Pediatrics, Umm AlQura University, Makkah, Saudi Arabia

Princess Noorah Oncology Center, King Abdulaziz Medical City, Jeddah, Saudi Arabia

Correspondence

Wasil Jastaniah, College of Medicine, Department of Pediatrics, Umm AlQura University and Princess Noorah Oncology Center, King Abdulaziz Medical City, P.O. Box 9515, Jeddah 21423, Saudi Arabia.

Email: [email protected]

Search for more papers by this author

First published: 14 December 2016

https://doi.org/10.1002/pbc.26385

Citations: 13

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Abstract

This report presents a case of Bloom syndrome (BS) in a consanguineous Saudi family. The patient, an 11-year-old male with mature B-cell lymphoma, had minimal therapeutic response and significant dose-limiting toxicity with standard chemotherapy treatment. He later responded successfully to a rituximab-based chemotherapy protocol. This case highlights that the rituximab-based chemotherapy protocol is an effective and safe treatment alternative for mature B-cell lymphoma in patients with BS. Further trials are warranted to investigate this modality of treatment.

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Volume64, Issue7

July 2017

e26385

Successful treatment of mature B-cell lymphoma with rituximab-based chemotherapy in a patient with Bloom syndrome

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Successful treatment of mature B-cell lymphoma with rituximab-based chemotherapy in a patient with Bloom syndrome

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