Effects of stretch and starvation on glucose uptake of rat soleus and extensor digitorum longus muscles

To examine the effects of stretch and starvation on muscle carbohydrate metabolism, glucose uptake was measured using [³H]3-O-methylglucose. Glucose uptake was higher in the stretched condition, and more so in soleus muscle than in extensor digitorum longus. After 4 days of starvation, glucose uptake decreased significantly in soleus muscle, but in extensor digitorum longus muscle, glucose uptake per noncollagen protein increased.