Clinical Research Article

Gender difference in clinical conditions among hospitalized adults with myotonic dystrophy

Corresponding Author

Lijing Ouyang PhD

[email protected]

Rare Disorders and Health Outcomes Team, Division of Human Development and Disability, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 1600 Clifton Road, MS E-88, Atlanta, Georgia 30329, USA

Correspondence to: L. Ouyang; e-mail: [email protected]Search for more papers by this author

Yinding Wang PhD,

Yinding Wang PhD

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Rodolfo Valdez PhD,

Rodolfo Valdez PhD

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Nicholas Johnson MD,

Nicholas Johnson MD

orcid.org/0000-0002-3917-4257

Department of Neurology, Virginia Commonwealth University, Virginia, USA

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Laurie Gutmann MD,

Laurie Gutmann MD

Department of Neurology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA

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Natalie Street MS,

Natalie Street MS

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Julie Bolen PhD,

Julie Bolen PhD

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Lijing Ouyang PhD,

Corresponding Author

Lijing Ouyang PhD

[email protected]

Correspondence to: L. Ouyang; e-mail: [email protected]Search for more papers by this author

Yinding Wang PhD,

Yinding Wang PhD

Search for more papers by this author

Rodolfo Valdez PhD,

Rodolfo Valdez PhD

Search for more papers by this author

Nicholas Johnson MD,

Nicholas Johnson MD

orcid.org/0000-0002-3917-4257

Department of Neurology, Virginia Commonwealth University, Virginia, USA

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Laurie Gutmann MD,

Laurie Gutmann MD

Department of Neurology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA

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Natalie Street MS,

Natalie Street MS

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Julie Bolen PhD,

Julie Bolen PhD

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First published: 21 December 2018

https://doi.org/10.1002/mus.26402

Citations: 6

Conflicts of Interest: None of the authors have any conflicts of interest to disclose.

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ABSTRACT

Introduction: In this study we examined gender differences in adult hospitalizations with myotonic dystrophy (DM). Methods: From the Nationwide Inpatient Sample (NIS) 2010–2014, we identified 1,891 adult hospitalizations with a DM diagnosis and constructed a comparison group of hospitalizations without DM using propensity score matching. We calculated relative risk by gender for 44 clinical diagnoses that each accounted for at least 5% of DM hospitalizations. Results: Hospitalizations with DM were longer (4.8 vs. 4.1 days, P < 0.0001) and more costly ($13,241 vs. $11,458, P < 0.0001) than those without DM. More than half (25 of 44) of the conditions co-occurring with DM hospitalizations did not differ in their relative risks by gender. For those that differed by gender, only 5 were specific to DM, compared with hospitalizations without DM. Discussion: Our findings highlight the importance of comprehensive and coordinated care for DM rather than gender-oriented care in the inpatient setting. Muscle Nerve 59:348–353, 2019

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REFERENCES

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Volume59, Issue3

March 2019

Pages 348-353

Gender difference in clinical conditions among hospitalized adults with myotonic dystrophy

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Gender difference in clinical conditions among hospitalized adults with myotonic dystrophy

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