Volume 86, Issue 5 pp. 2766-2779
FULL PAPER

Marmoset brain segmentation from deconvolved magnetic resonance images and estimated label maps

Farah Bazzi

Corresponding Author

Farah Bazzi

Computer Science Research Institute of Toulouse (IRIT), Toulouse University UPS, CNRS, UMR, Toulouse, France

Centre de Recherche Cerveau et Cognition (CerCo), Université de Toulouse UPS, CNRS, UMR, Toulouse, France

Doctoral School of Sciences and Technology, AZM Center for Research in Biotechnology and Its Applications, Lebanese University, Beirut, Lebanon

Correspondence

Farah Bazzi, Institut de Recherche en Informatique de Toulouse (IRIT), Université de Toulouse UPS, CNRS, UMR 5505, Toulouse, France.

Email: [email protected]

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Muriel Mescam

Muriel Mescam

Centre de Recherche Cerveau et Cognition (CerCo), Université de Toulouse UPS, CNRS, UMR, Toulouse, France

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Ahmad Diab

Ahmad Diab

Doctoral School of Sciences and Technology, AZM Center for Research in Biotechnology and Its Applications, Lebanese University, Beirut, Lebanon

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Omar Falou

Omar Falou

Doctoral School of Sciences and Technology, AZM Center for Research in Biotechnology and Its Applications, Lebanese University, Beirut, Lebanon

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Hassan Amoud

Hassan Amoud

Doctoral School of Sciences and Technology, AZM Center for Research in Biotechnology and Its Applications, Lebanese University, Beirut, Lebanon

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Adrian Basarab

Adrian Basarab

Computer Science Research Institute of Toulouse (IRIT), Toulouse University UPS, CNRS, UMR, Toulouse, France

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Denis Kouamé

Denis Kouamé

Computer Science Research Institute of Toulouse (IRIT), Toulouse University UPS, CNRS, UMR, Toulouse, France

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First published: 25 June 2021

Funding information

The AZM and SAADE Association and the Doctoral School of Science and Technology, Lebanon

Abstract

Purpose

The proposed method aims to create label maps that can be used for the segmentation of animal brain MR images without the need of a brain template. This is achieved by performing a joint deconvolution and segmentation of the brain MR images.

Methods

It is based on modeling locally the image statistics using a generalized Gaussian distribution (GGD) and couples the deconvolved image and its corresponding labels map using the GGD-Potts model. Because of the complexity of the resulting Bayesian estimators of the unknown model parameters, a Gibbs sampler is used to generate samples following the desired posterior probability.

Results

The performance of the proposed algorithm is assessed on simulated and real MR images by the segmentation of enhanced marmoset brain images into its main compartments using the corresponding label maps created. Quantitative assessment showed that this method presents results that are comparable to those obtained with the classical method—registering the volumes to a brain template.

Conclusion

The proposed method of using labels as prior information for brain segmentation provides a similar or a slightly better performance compared with the classical reference method based on a dedicated template.

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