Volume 69, Issue 1 pp. 103-113
Full Paper

Super-resolution for multislice diffusion tensor imaging

Dirk H. J. Poot

Dirk H. J. Poot

Departments of Medical informatics and Radiology, BIGR, Erasmus Medical Center, Rotterdam, the Netherlands

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Ben Jeurissen

Ben Jeurissen

IBBT-Vision Lab, Department of Physics, Vision Lab, University of Antwerp, Antwerp, Belgium

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Yannick Bastiaensen

Yannick Bastiaensen

IBBT-Vision Lab, Department of Physics, Vision Lab, University of Antwerp, Antwerp, Belgium

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Jelle Veraart

Jelle Veraart

IBBT-Vision Lab, Department of Physics, Vision Lab, University of Antwerp, Antwerp, Belgium

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Wim Van Hecke

Wim Van Hecke

IBBT-Vision Lab, Department of Physics, Vision Lab, University of Antwerp, Antwerp, Belgium

Department of Radiology, University Hospital Antwerp, University of Antwerp, Edegem (Antwerp), Belgium

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Paul M. Parizel

Paul M. Parizel

Department of Radiology, University Hospital Antwerp, University of Antwerp, Edegem (Antwerp), Belgium

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Jan Sijbers

Corresponding Author

Jan Sijbers

IBBT-Vision Lab, Department of Physics, Vision Lab, University of Antwerp, Antwerp, Belgium

Department of Physics, Vision Lab, University of Antwerp, Universiteitsplein 1, N 1.13, B-2610 Antwerp, Belgium===Search for more papers by this author
First published: 12 March 2012
Citations: 49

Abstract

Diffusion weighted magnetic resonance images are often acquired with single shot multislice imaging sequences, because of their short scanning times and robustness to motion. To minimize noise and acquisition time, images are generally acquired with either anisotropic or isotropic low resolution voxels, which impedes subsequent posterior image processing and visualization. In this article, we propose a super-resolution method for diffusion weighted imaging that combines anisotropic multislice images to enhance the spatial resolution of diffusion tensor data. Each diffusion weighted image is reconstructed from a set of arbitrarily oriented images with a low through-plane resolution. The quality of the reconstructed diffusion weighted images was evaluated by diffusion tensor metrics and tractography. Experiments with simulated data, a hardware DTI phantom, as well as in vivo human brain data were conducted. Our results show a significant increase in spatial resolution of the diffusion tensor data while preserving high signal to noise ratio. Magn Reson Med, 2013. © 2012 Wiley Periodicals, Inc.

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