Optically detunable, inductively coupled coil for self-gating in small animal magnetic resonance imaging
Matthias Korn
Department of Medical Physics in Radiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany
Imagerie par Résonance Magnétique Médicale et Multi-Modalités, UMR 8081, CNRS-Université Paris-Sud XI, Orsay, France
Search for more papers by this authorReiner Umathum
Department of Medical Physics in Radiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany
Search for more papers by this authorJessica Schulz
Department of Medical Physics in Radiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany
Department of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
Search for more papers by this authorWolfhard Semmler
Department of Medical Physics in Radiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany
Search for more papers by this authorCorresponding Author
Michael Bock
Department of Medical Physics in Radiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany
German Cancer Research Center (DKFZ), Department Medical Physics in Radiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany===Search for more papers by this authorMatthias Korn
Department of Medical Physics in Radiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany
Imagerie par Résonance Magnétique Médicale et Multi-Modalités, UMR 8081, CNRS-Université Paris-Sud XI, Orsay, France
Search for more papers by this authorReiner Umathum
Department of Medical Physics in Radiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany
Search for more papers by this authorJessica Schulz
Department of Medical Physics in Radiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany
Department of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
Search for more papers by this authorWolfhard Semmler
Department of Medical Physics in Radiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany
Search for more papers by this authorCorresponding Author
Michael Bock
Department of Medical Physics in Radiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany
German Cancer Research Center (DKFZ), Department Medical Physics in Radiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany===Search for more papers by this authorAbstract
An inductively coupled coil concept is presented, which improves the compensation of physiological motion by the self-gating (SG) technique. The animal is positioned in a conventional volume coil encompassing the whole animal. A small, resonant surface coil (SG-coil) is placed on the thorax so that its sensitive region includes the heart. Via inductive coupling the SG-coil amplifies selectively the MR signal of the beating heart. With an optical detuning mechanism, this coupling can be switched off during acquisition of the MR image information, whereas it is active during SG data sampling to provide the physiological information. In vivo experiments on a mouse show an amplification of the SG signal by at least 40%. Magn Reson Med, 2011. © 2010 Wiley-Liss, Inc.
REFERENCES
- 1 Wendt RE III, Rokey R, Vick GW III, Johnston DL. Electrocardiographic gating and monitoring in NMR imaging. Magn Reson Imaging 1988; 6: 89–95.
- 2 Rokey R, Wendt RE, Johnston DL. Monitoring of acutely Ill patients during nuclear magnetic resonance imaging: use of a time-varying filter electrocardiographic gating device to reduce gradient artifacts. Magn Reson Med 1988; 6: 240–245.
- 3 Polson MJR, Barker AT, Gardiner S. The effect of rapid rise-time magnetic fields on the ECG of the rat. Clin Phys Physiol Meas 1982; 3: 231–234.
- 4 Togawa T, Okai O, Oshima M. Observation of blood Flow EMF in externally applied strong magnetic field by surface electrodes. Med Biol Eng 1967; 5: 169–170.
- 5 Tenforde TS. Magnetically induced electric fields and currents in the circulatory system. Prog Biophys Mol Biol 2005; 87: 279–288.
- 6 Keltner JR, Roos MS, Brakeman PR, Budinger TF. Magnetohydrodynamics of blood flow. Magn Reson Med 1990; 16: 139–149.
- 7 Brau AC, Brittain JH. Generalized self-navigated motion detection technique: Preliminary investigation in abdominal imaging. Magn Reson Med 2006; 55: 263–270.
- 8 Crowe ME, Larson AC, Zhang Q, Carr J, White RD, Li D, Simonetti OP. Automated rectilinear self-gated cardiac cine imaging. Magn Reson Med 2004; 52: 782–788.
- 9 Porter JR, Wright SM, Famili N. A four-channel time domain multiplexer: a cost-effective alternative to multiple receivers. Magn Reson Med 1994; 32: 499–504.
- 10 Zuehlsdorff S, Umathum R, Volz S, Hallscheidt P, Fink C, Semmler W, Bock M. MR coil design for simultaneous tip tracking and curvature delineation of a catheter. Magn Reson Med 2004; 52: 214–218.
- 11 Boskamp EB. Improved surface coil imaging in MR: decoupling of the excitation and receiver coils. Radiology 1985; 157: 449–452.
- 12 Edelstein WA, Hardy CJ, Mueller OM. Electronic decoupling of surface-coil receivers for NMR imaging and spectroscopy. J Magn Reson 1986; 67: 156–161.
- 13 Wong EY, Zhang Q, Duerk, JL, Lewin JS, Wendt M. An optical system for wireless detuning of parallel resonant circuits. J Magn Reson Imaging 2000; 12: 632–638.
- 14 Weiss S, Kuehne T, Brinkert F, Krombach G, Katoh M, Schaeffter T, Guenther RW, Buecker A. In vivo safe catheter visualization and slice tracking using an optically detunable resonant marker. Magn Reson Med 2004; 52: 860–868.
- 15 Hoult DI, Richards RE. The signal-to-noise ratio of the nuclear magnetic resonance experiment. J Magn Reson 1976; 24: 71–85.
- 16 Hoult DI. The principle of reciprocity in signal strength calculations-a mathematical guide. Concepts Magn Reson 2000; 12: 173–187.
- 17 Terman FE. Electronic and radio engineering, 4th ed. New York: McGraw-Hill Book Company; 1955.
- 18 Hoult DI, Tomanek B. Use of mutually inductive coupling in probe design. Concepts Magn Reson 2002; 15: 262–285.
- 19 Roemer PB, Edelstein WA, Hayes CE, Souza SP, Mueller OM. The NMR Phased Array. Magn Reson Med 1990; 16: 192–225.
- 20 Schulz J, Korn M, Deimling M, Semmler W, Bock M. Flow-compensated self-gating. MAGMA 2008; 21: 307–315.
- 21 Nijm GM, Sahakian AV, Swiryn S, Larson AC. Comparison of signal peak algorithms for self-gated cardiac CINE MRI. Comput Cardiol 2007; 34: 407–410.
- 22
Barberi EA,
Gati JS,
Rutt BK,
Menon RS.
A transmit-only/ receive-only (TORO) RF system for high-field MRI/MRS applications.
Magn Reson Med
2000;
43:
284–289.
10.1002/(SICI)1522-2594(200002)43:2<284::AID-MRM16>3.0.CO;2-C CAS PubMed Web of Science® Google Scholar
- 23 Ledden PJ, Gelderen PV, Duyn J. Birdcage volume transmit, eight channel receive array system for brain imaging at 7T. In Proceedings of the 13th Annual Meeting of ISMRM, Miami, USA; 2005. pp 322.
- 24 Kugel H, Bremer C, Puschel M, Fischbach R, Lenzen H, Tombach B, Van Aken H, Heindel W. Hazardous situation in the MR bore: induction in ECG leads causes fire. Eur Radiol 2003; 13: 690–694.
