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Optimized interleaved whole-brain 3D double inversion recovery (DIR) sequence for imaging the neocortex

Corresponding Author

P.A. Boulby

[email protected]

Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, UK

MRI Unit, National Society for Epilepsy, Chalfont Centre for Epilepsy, Chalfont St. Peter, Gerrards Cross, Buckinghamshire, SL9 0RJ, UK===Search for more papers by this author

M.R. Symms,

M.R. Symms

Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, UK

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G.J. Barker,

G.J. Barker

Department of Neuroinflammation, Institute of Neurology, University College London, London, UK

Neuroimaging Research Group, Kings College London, Institute of Psychiatry, London, UK

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P.A. Boulby,

Corresponding Author

P.A. Boulby

[email protected]

Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, UK

MRI Unit, National Society for Epilepsy, Chalfont Centre for Epilepsy, Chalfont St. Peter, Gerrards Cross, Buckinghamshire, SL9 0RJ, UK===Search for more papers by this author

M.R. Symms,

M.R. Symms

Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, UK

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G.J. Barker,

G.J. Barker

Department of Neuroinflammation, Institute of Neurology, University College London, London, UK

Neuroimaging Research Group, Kings College London, Institute of Psychiatry, London, UK

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First published: 24 May 2004

https://doi.org/10.1002/mrm.20088

Citations: 26

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Abstract

For a substantial number of individuals with neurological disorders, a conventional MRI scan does not reveal any obvious etiology; however, it is believed that abnormalities in the neocortical gray matter (GM) underlie many of these disorders. Attempts to image the neocortex are hindered by its thin, convoluted structure, and the partial volume (PV) effect. Therefore, we developed a 3D version of the double inversion recovery (DIR) sequence that incorporates an optimized interleaved (OIL) strategy to improve efficiency and allow high-quality, high-resolution imaging of GM. Magn Reson Med 51:1181–1186, 2004. © 2004 Wiley-Liss, Inc.

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Volume51, Issue6

June 2004

Pages 1181-1186

Optimized interleaved whole-brain 3D double inversion recovery (DIR) sequence for imaging the neocortex

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Optimized interleaved whole-brain 3D double inversion recovery (DIR) sequence for imaging the neocortex

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