Photooxidation of Nanopatterned Poly(chloromethylstyrene): Direct Formation of Crosslinked Aldehyde-Functionalized Films for Chemical Functionalization and Bioconjugation
Xi Yu
Department of Chemistry, University of Massachusetts, 710 North Pleasant St. Amherst, MA 01003, USA
Search for more papers by this authorChandramouleeswaran Subramani
Department of Chemistry, University of Massachusetts, 710 North Pleasant St. Amherst, MA 01003, USA
Search for more papers by this authorXiaochao Yang
College of Bioengineering and Microsystem Research Center, Chongqing University, Chongqing, 400044, P. R. China
Search for more papers by this authorChae Kyu Kim
Department of Chemistry, University of Massachusetts, 710 North Pleasant St. Amherst, MA 01003, USA
Search for more papers by this authorCorresponding Author
Vincent M. Rotello
Department of Chemistry, University of Massachusetts, 710 North Pleasant St. Amherst, MA 01003, USA
Department of Chemistry, University of Massachusetts, 710 North Pleasant St. Amherst, MA 01003, USA.Search for more papers by this authorXi Yu
Department of Chemistry, University of Massachusetts, 710 North Pleasant St. Amherst, MA 01003, USA
Search for more papers by this authorChandramouleeswaran Subramani
Department of Chemistry, University of Massachusetts, 710 North Pleasant St. Amherst, MA 01003, USA
Search for more papers by this authorXiaochao Yang
College of Bioengineering and Microsystem Research Center, Chongqing University, Chongqing, 400044, P. R. China
Search for more papers by this authorChae Kyu Kim
Department of Chemistry, University of Massachusetts, 710 North Pleasant St. Amherst, MA 01003, USA
Search for more papers by this authorCorresponding Author
Vincent M. Rotello
Department of Chemistry, University of Massachusetts, 710 North Pleasant St. Amherst, MA 01003, USA
Department of Chemistry, University of Massachusetts, 710 North Pleasant St. Amherst, MA 01003, USA.Search for more papers by this authorAbstract
UV irradiation of chloromethyl styrene simultaneously crosslinks the polymer and generates aldehyde groups that can be employed for polymer surface functionalization through aldehyde-imine/hydrazone chemistry. Using this method, we successfully have functionalized nanoimprinted polymer patterns with dyes, nanoparticles, and enzymes. These surfaces were characterized by infrared (ATR-IR) spectroscopy, X-ray photoelectron spectroscopy (XPS), fluorescence microscopy, and enzymatic activity assays.
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