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Clinical and preclinical photodynamic therapy
Dr. Anita M. R. Fisher PhD,
A. Linn Murphree MD,
Charles J. Gomer PhD,
Corresponding Author
Dr. Anita M. R. Fisher PhD
Clayton Ocular Oncology Center, Childrens Hospital Los Angeles, California 90027
Departments of Pediatrics, Ophthalmology, and Radiation Oncology, University of Southern California School of Medicine, Los Angeles, California 90027
Childrens Hospital Los Angeles, Mail Stop #67, 4650 Sunset Boulevard, Los Angeles, CA 90027Search for more papers by this authorA. Linn Murphree MD
Clayton Ocular Oncology Center, Childrens Hospital Los Angeles, California 90027
Departments of Pediatrics, Ophthalmology, and Radiation Oncology, University of Southern California School of Medicine, Los Angeles, California 90027
Search for more papers by this authorCharles J. Gomer PhD
Clayton Ocular Oncology Center, Childrens Hospital Los Angeles, California 90027
Departments of Pediatrics, Ophthalmology, and Radiation Oncology, University of Southern California School of Medicine, Los Angeles, California 90027
Search for more papers by this authorDr. Anita M. R. Fisher PhD,
A. Linn Murphree MD,
Charles J. Gomer PhD,
Corresponding Author
Dr. Anita M. R. Fisher PhD
Clayton Ocular Oncology Center, Childrens Hospital Los Angeles, California 90027
Departments of Pediatrics, Ophthalmology, and Radiation Oncology, University of Southern California School of Medicine, Los Angeles, California 90027
Childrens Hospital Los Angeles, Mail Stop #67, 4650 Sunset Boulevard, Los Angeles, CA 90027Search for more papers by this authorA. Linn Murphree MD
Clayton Ocular Oncology Center, Childrens Hospital Los Angeles, California 90027
Departments of Pediatrics, Ophthalmology, and Radiation Oncology, University of Southern California School of Medicine, Los Angeles, California 90027
Search for more papers by this authorCharles J. Gomer PhD
Clayton Ocular Oncology Center, Childrens Hospital Los Angeles, California 90027
Departments of Pediatrics, Ophthalmology, and Radiation Oncology, University of Southern California School of Medicine, Los Angeles, California 90027
Search for more papers by this authorAbstract
Photodynamic therapy (PDT) is a treatment modality that utilizes a photosensitizing drug activated by laser generated light, and is proving effective for oncologic and nononcologic applications. This report provides an overview of photosensitizers, photochemistry, photobiology, and the lasers involved in photodynamic therapy. Clinical and preclinical PDT studies involving Photofrin and various second generation photosensitizers are reviewed. © 1995 Wiley-Liss, Inc.
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