Otology/Neurotology

Palatal botulinum toxin as a novel therapy for objective tinnitus in forced eyelid closure syndrome

Thomas M. Kaffenberger BS

University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, U.S.A.

Rajarsi Mandal MD

Head and Neck Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, U.S.A.

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Barry M. Schaitkin MD,

Barry M. Schaitkin MD

Department of Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, U.S.A.

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Barry E. Hirsch MD,

Corresponding Author

Barry E. Hirsch MD

[email protected]

Department of Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, U.S.A.

Send correspondence to Dr. Barry E. Hirsch, M.D., F.A.C.S., Department of Otolaryngology, University of Pittsburgh Medical Center, Suite 500 Eye and Ear Institute, 200 Lothrop Street, Pittsburgh, PA 15213. E-mail: [email protected]Search for more papers by this author

Thomas M. Kaffenberger BS,

Thomas M. Kaffenberger BS

University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, U.S.A.

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Rajarsi Mandal MD,

Rajarsi Mandal MD

Head and Neck Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, U.S.A.

Search for more papers by this author

Barry M. Schaitkin MD,

Barry M. Schaitkin MD

Department of Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, U.S.A.

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Barry E. Hirsch MD,

Corresponding Author

Barry E. Hirsch MD

[email protected]

Department of Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, U.S.A.

First published: 26 September 2016

https://doi.org/10.1002/lary.26191

Citations: 4

The authors have no funding, financial relationships, or conflicts of interest to disclose. Additional supporting information may be found in the online version of this article.

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Abstract

Objective tinnitus associated with eyelid closure is a rare clinical entity with only a few reported cases. This association previously was identified as forced eyelid closure syndrome (FECS) and involves an aberrant neural reflex between cranial nerve VII (activating the orbicularis oculi muscle) and cranial nerve V (activating the tensor tympani muscle). We present a 52-year-old Caucasian female with a 2-month history of FECS who was successfully treated with intrapalatal botulinum toxin, with full resolution of her objective tinnitus symptoms. This is the first reported use of botulinum toxin in FECS. Laryngoscope, 127:1199–1201, 2017

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BIBLIOGRAPHY

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Citing Literature

Volume127, Issue5

May 2017

Pages 1199-1201

Filename	Description
lary26191-sup-0001-suppm1.MOV1.1 MB	Supp. Video: Nasopharyngoscopy rotated at 90° demonstrates inducible, unilateral soft palate contraction with patient blinking. Botulinum toxin was injected into the center of palatal contraction, alleviating her symptoms.
lary26191-sup-0002-suppt2.docx16.9 KB	Supplementary Table 1
lary26191-sup-0003-suppm3.docx16.9 KB	Supplementary Table 2

Palatal botulinum toxin as a novel therapy for objective tinnitus in forced eyelid closure syndrome

Abstract

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Palatal botulinum toxin as a novel therapy for objective tinnitus in forced eyelid closure syndrome

Abstract

Supporting Information

BIBLIOGRAPHY

Citing Literature

References

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