Volume 121, Issue 8 pp. 1627-1630
General Otolaryngology

Varicella zoster virus infection of the pharynx and larynx with multiple cranial neuropathies

Yuan-Yung Lin MD

Yuan-Yung Lin MD

Department of Otolaryngology—Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China

Search for more papers by this author
Chuan-Hsiang Kao MD

Chuan-Hsiang Kao MD

Department of Otolaryngology—Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China

Search for more papers by this author
Chih-Hung Wang MD, PhD

Corresponding Author

Chih-Hung Wang MD, PhD

Department of Otolaryngology—Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China

Institute of Microbiology and Immunology, National Defense Medical Center, Taipei, Taiwan, Republic of China

Institute of Undersea and Hyperbaric Medicine, National Defense Medical Center, Taipei, Taiwan, Republic of China

Department of Otolaryngology—Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, 325, Sec. 2, Cheng-Kung Rd., Neihu District, Taipei 114, Taipei, Taiwan, Republic of ChinaSearch for more papers by this author
First published: 25 July 2011
Citations: 33

The authors have no financial disclosures for this article.

The authors have no conflits of interest to declare.

Abstract

Varicella zoster virus (VZV) infection of the head and neck region may present with various clinical symptoms, involving different entities and different routes of viral spreading. We present a case of VZV infection of the pharynx and larynx with multiple cranial nerve (CN) neuropathies (CN VII, VIII, IX, and X) of a 52-year-old woman who complained of the sudden onset of hoarseness, odynophagia, dysphagia, and hearing loss in the left ear, followed by left-side facial weakness lasting for 1 week. Endoscopic examination revealed multiple mucosal erosions over the oropharynx, with extension upward to the nasopharynx and downward to the mucosa overlying the epiglottis, arytenoid, and vocal cord. All of these lesions tended to lateralize to the left side, suggesting a VZV infection diagnosis; this was confirmed by polymerase chain reaction on eruptional exudates, as well as serologic examination.

The full text of this article hosted at iucr.org is unavailable due to technical difficulties.