Head and Neck

Parapharyngeal space pleomorphic adenoma: A 30-year review^†

Abie H. Mendelsohn MD

Division of Head and Neck Surgery, University of California Los Angeles School of Medicine, Los Angeles, California, U.S.A

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Sunita Bhuta MD,

Sunita Bhuta MD

Department of Pathology and Laboratory Medicine, University of California Los Angeles School of Medicine, Los Angeles, California, U.S.A

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Thomas C. Calcaterra MD,

Thomas C. Calcaterra MD

Division of Head and Neck Surgery, University of California Los Angeles School of Medicine, Los Angeles, California, U.S.A

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Hubert B. Shih BS,

Hubert B. Shih BS

Division of Head and Neck Surgery, University of California Los Angeles School of Medicine, Los Angeles, California, U.S.A

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Elliot Abemayor MD, PhD,

Elliot Abemayor MD, PhD

Division of Head and Neck Surgery, University of California Los Angeles School of Medicine, Los Angeles, California, U.S.A

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Maie A. St. John MD, PhD,

Corresponding Author

Maie A. St. John MD, PhD

[email protected]

Division of Head and Neck Surgery, University of California Los Angeles School of Medicine, Los Angeles, California, U.S.A

Division of Head & Neck Surgery, UCLA Medical Center, 10833 Le Conte Ave., Rm. 62-132 CHS, Los Angeles, CA 90095Search for more papers by this author

Abie H. Mendelsohn MD,

Abie H. Mendelsohn MD

Division of Head and Neck Surgery, University of California Los Angeles School of Medicine, Los Angeles, California, U.S.A

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Sunita Bhuta MD,

Sunita Bhuta MD

Department of Pathology and Laboratory Medicine, University of California Los Angeles School of Medicine, Los Angeles, California, U.S.A

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Thomas C. Calcaterra MD,

Thomas C. Calcaterra MD

Division of Head and Neck Surgery, University of California Los Angeles School of Medicine, Los Angeles, California, U.S.A

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Hubert B. Shih BS,

Hubert B. Shih BS

Division of Head and Neck Surgery, University of California Los Angeles School of Medicine, Los Angeles, California, U.S.A

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Elliot Abemayor MD, PhD,

Elliot Abemayor MD, PhD

Division of Head and Neck Surgery, University of California Los Angeles School of Medicine, Los Angeles, California, U.S.A

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Maie A. St. John MD, PhD,

Corresponding Author

Maie A. St. John MD, PhD

[email protected]

Division of Head and Neck Surgery, University of California Los Angeles School of Medicine, Los Angeles, California, U.S.A

Division of Head & Neck Surgery, UCLA Medical Center, 10833 Le Conte Ave., Rm. 62-132 CHS, Los Angeles, CA 90095Search for more papers by this author

First published: 12 October 2009

https://doi.org/10.1002/lary.20496

Citations: 43

^†

Presented at the Triological Society Combined Sections Meeting, Phoenix, Arizona, U.S.A., May 28–31, 2009.

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Abstract

Objectives/Hypothesis:

To evaluate the treatment results of pleomorphic adenoma (PA) of the parapharyngeal space at a single institution during a 30-year period.

Study Design:

A retrospective review.

Methods:

This study was performed by examining the records and reviewing the pathology of 44 patients with PA of the parapharyngeal space treated at a single medical center from January 1975 to November 2005.

Results:

Of the 44 patients with PA, 35 patients underwent 38 excisions. Eleven men and 27 women were treated surgically. Follow-up varied from 24 months to 180 months. There were three recurrences in two patients. Recurrence rates at 5 and 10 years were equal at 7.9%. Gender, age, tumor volume, surgical approach, pathologic surgical margin status, and prior resections were evaluated for significant prognostic factors. Advanced age proved a poor prognostic indicator (P < .05). History of prior resection (P < .01) was significant for recurrence. Positive surgical margins (P = .69) proved a negative association.

Conclusions:

We report low recurrence rates in this patient population with two important prognostic indicators. History of prior resection is significant to predict recurrence. Interestingly, positive surgical margins are actually shown not to effect risk of recurrence. Local recurrence of the tumor is associated with further recurrence and less favorable prognosis. Laryngoscope, 2009

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Citing Literature

Volume119, Issue11

November 2009

Pages 2170-2174

Parapharyngeal space pleomorphic adenoma: A 30-year review^†

Abstract

Objectives/Hypothesis:

Study Design:

Methods:

Results:

Conclusions:

BIBLIOGRAPHY

Citing Literature

References

Information

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Parapharyngeal space pleomorphic adenoma: A 30-year review†

Abstract

Objectives/Hypothesis:

Study Design:

Methods:

Results:

Conclusions:

BIBLIOGRAPHY

Citing Literature

References

Related

Information

Parapharyngeal space pleomorphic adenoma: A 30-year review^†