Volume 42, Issue 1 pp. 221-231

Original Article

Compression Elastography and Shear Wave Ultrasound Elastography for Measurement of Brain Elasticity in Full-Term and Premature Neonates

A Prospective Study

Huihui Yang MS,

Huihui Yang MS

Department of Medical Imaging Center, The First Affiliated Hospital of Jinan University, Guangdong, China

Department of Ultrasound Medicine, The Third Affiliated Hospital of Guangzhou Medical University, Guangdong, China

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Huibing Li MS,

Huibing Li MS

Department of Neurosurgery, Guangdong 999 Brain Hospital, Guangdong, China

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Jianyi Liao MS,

Jianyi Liao MS

Department of Ultrasound Medicine, The Third Affiliated Hospital of Guangzhou Medical University, Guangdong, China

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Xiaoyan Yuan BS,

Xiaoyan Yuan BS

Department of Ultrasound Medicine, The Third Affiliated Hospital of Guangzhou Medical University, Guangdong, China

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Changzheng Shi MD,

Corresponding Author

Changzheng Shi MD

[email protected]

orcid.org/0000-0003-4582-0769

Department of Medical Imaging Center, The First Affiliated Hospital of Jinan University, Guangdong, China

Address correspondence to Changzheng Shi, MD, Department of Medical Imaging Center, The First Affiliated Hospital of Jinan University, 613 West Huangpu Avenue, Tianhe District, Guangzhou, Guangdong, China.

E-mail: [email protected]

Weixiang Liang, MS, Department of Ultrasound Medicine, The Third Affiliated Hospital of Guangzhou Medical University, 63 Duobao Road, Liwan District, Guangzhou, Guangdong, China.

E-mail: [email protected]

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Weixiang Liang MS,

Corresponding Author

Weixiang Liang MS

[email protected]

orcid.org/0000-0001-7858-4921

Department of Ultrasound Medicine, The Third Affiliated Hospital of Guangzhou Medical University, Guangdong, China

E-mail: [email protected]

Weixiang Liang, MS, Department of Ultrasound Medicine, The Third Affiliated Hospital of Guangzhou Medical University, 63 Duobao Road, Liwan District, Guangzhou, Guangdong, China.

E-mail: [email protected]

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Huihui Yang MS,

Huihui Yang MS

Department of Medical Imaging Center, The First Affiliated Hospital of Jinan University, Guangdong, China

Department of Ultrasound Medicine, The Third Affiliated Hospital of Guangzhou Medical University, Guangdong, China

Search for more papers by this author

Huibing Li MS,

Huibing Li MS

Department of Neurosurgery, Guangdong 999 Brain Hospital, Guangdong, China

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Jianyi Liao MS,

Jianyi Liao MS

Department of Ultrasound Medicine, The Third Affiliated Hospital of Guangzhou Medical University, Guangdong, China

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Xiaoyan Yuan BS,

Xiaoyan Yuan BS

Department of Ultrasound Medicine, The Third Affiliated Hospital of Guangzhou Medical University, Guangdong, China

Search for more papers by this author

Changzheng Shi MD,

Corresponding Author

Changzheng Shi MD

[email protected]

orcid.org/0000-0003-4582-0769

Department of Medical Imaging Center, The First Affiliated Hospital of Jinan University, Guangdong, China

E-mail: [email protected]

Weixiang Liang, MS, Department of Ultrasound Medicine, The Third Affiliated Hospital of Guangzhou Medical University, 63 Duobao Road, Liwan District, Guangzhou, Guangdong, China.

E-mail: [email protected]

Search for more papers by this author

Weixiang Liang MS,

Corresponding Author

Weixiang Liang MS

[email protected]

orcid.org/0000-0001-7858-4921

Department of Ultrasound Medicine, The Third Affiliated Hospital of Guangzhou Medical University, Guangdong, China

E-mail: [email protected]

Weixiang Liang, MS, Department of Ultrasound Medicine, The Third Affiliated Hospital of Guangzhou Medical University, 63 Duobao Road, Liwan District, Guangzhou, Guangdong, China.

E-mail: [email protected]

Search for more papers by this author

First published: 04 August 2022

https://doi.org/10.1002/jum.16075

Citations: 2

This study was supported by the Youth Foundation of the Third Affiliated Hospital of Guangzhou Medical University (2017Q10) and the Medical Science and Technology Research Foundation of Guangdong Province (2019298).

Huihui Yang and Huibing Li have contributed equally to this work and share first authorship.

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Abstract

Objectives

To investigate the brain tissue elasticity in normal term and premature neonates using compression elastography and shear wave elastography.

Methods

This prospective observational study enrolled term and premature neonates admitted to the Third Affiliated Hospital of Guangzhou Medical University between July 2019 and December 2020.

Results

A total of 106 neonates, including 65 premature neonates and 41 term neonates, were enrolled. The elastic modulus of the frontal white matter in males was significantly lower than in females (11.67 ± 0.98 versus 12.25 ± 1.31, P = .030), but the shear wave velocity of the thalamus in males was significantly lower than in females (1.18 ± 0.13 versus 1.82 ± 0.10, P < .001). There was no significant correlation between real-time body weight and brain tissue elasticity including elastic modulus and shear wave velocity. But, the shear wave velocity of parietal white matter (r = 0.319, P = .014) and thalamus (r = −0.268, P = .040) and the elastic modulus of parietal white matter (r = 0.356, P = .006) were correlated with corrected gestational age.

Conclusions

Clinicians may consider using elastography to determine brain tissue elasticity in term and preterm neonates.

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Citing Literature

Volume42, Issue1

January 2023

Pages 221-231

Compression Elastography and Shear Wave Ultrasound Elastography for Measurement of Brain Elasticity in Full-Term and Premature Neonates

A Prospective Study

Abstract

Objectives

Methods

Results

Conclusions

References

Citing Literature

References

Information

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Compression Elastography and Shear Wave Ultrasound Elastography for Measurement of Brain Elasticity in Full-Term and Premature Neonates

A Prospective Study

Abstract

Objectives

Methods

Results

Conclusions

References

Citing Literature

References

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