Volume 35, Issue 2 pp. 120-123
Article
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Bladder cancer detection and surveillance: Carcinoembryonic antigen as a monitor of neoplastic transformation

Michel Boileau MD

Corresponding Author

Michel Boileau MD

Department of Urology, University of Washington School of Medicine

Division of Urology, University of Texas Health Science Center at Houston Medical School, 6431 Fannin, Suite 6018, Houston, TX 77030Search for more papers by this author
Douglas Swartz MD

Douglas Swartz MD

Department of Urology, University Hospital, Jacksonville, Florida

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Karmen Schmidt PhD

Karmen Schmidt PhD

Department of Pathology, University of Texas Health Science Center at Houston

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Waldemar Schmidt MD, PhD

Waldemar Schmidt MD, PhD

Department of Pathology, University of Texas Health Science Center at Houston

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First published: June 1987
Citations: 1

Abstract

Routine cytopathology of exfoliated urothelial cells will identify only 70% of patients with transitional cell carcinoma (TCC) because most welldifferentiated bladder tumors are not detected. Carcinoembryonic antigen (CEA) was identified on urothelial cancer cells from 66% of patients with grade I TCC, 65% with grade II TCC, 65% with grade III TCC, and 80% of patients with CIS. Immunoperoxidase labelling of CEA can enhance the sensitivity of exfoliative cytology.

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