An experimental brain tumor model in rabbits
David F. Morgan MD
Divisions of Neurosurgery and Oncology, Departments of Surgery and Radiation Oncology, UCLA School of Medicine, University of California, Los Angeles, and Surgical Service, Sepulveda Veterans Administration Medical Center, Sepulveda, California
Search for more papers by this authorCorresponding Author
Allan W. Silberman MD, PhD
Divisions of Neurosurgery and Oncology, Departments of Surgery and Radiation Oncology, UCLA School of Medicine, University of California, Los Angeles, and Surgical Service, Sepulveda Veterans Administration Medical Center, Sepulveda, California
54–140 CHS, UCLA School of Medicine, University of California, Los Angeles, CA 90024Search for more papers by this authorJ. Eric Bubbers PhD
Divisions of Neurosurgery and Oncology, Departments of Surgery and Radiation Oncology, UCLA School of Medicine, University of California, Los Angeles, and Surgical Service, Sepulveda Veterans Administration Medical Center, Sepulveda, California
Search for more papers by this authorRobert W. Rand MD, PhD
Divisions of Neurosurgery and Oncology, Departments of Surgery and Radiation Oncology, UCLA School of Medicine, University of California, Los Angeles, and Surgical Service, Sepulveda Veterans Administration Medical Center, Sepulveda, California
Search for more papers by this authorF. Kristian Storm MD
Divisions of Neurosurgery and Oncology, Departments of Surgery and Radiation Oncology, UCLA School of Medicine, University of California, Los Angeles, and Surgical Service, Sepulveda Veterans Administration Medical Center, Sepulveda, California
Search for more papers by this authorDonald L. Morton MD
Divisions of Neurosurgery and Oncology, Departments of Surgery and Radiation Oncology, UCLA School of Medicine, University of California, Los Angeles, and Surgical Service, Sepulveda Veterans Administration Medical Center, Sepulveda, California
Search for more papers by this authorDavid F. Morgan MD
Divisions of Neurosurgery and Oncology, Departments of Surgery and Radiation Oncology, UCLA School of Medicine, University of California, Los Angeles, and Surgical Service, Sepulveda Veterans Administration Medical Center, Sepulveda, California
Search for more papers by this authorCorresponding Author
Allan W. Silberman MD, PhD
Divisions of Neurosurgery and Oncology, Departments of Surgery and Radiation Oncology, UCLA School of Medicine, University of California, Los Angeles, and Surgical Service, Sepulveda Veterans Administration Medical Center, Sepulveda, California
54–140 CHS, UCLA School of Medicine, University of California, Los Angeles, CA 90024Search for more papers by this authorJ. Eric Bubbers PhD
Divisions of Neurosurgery and Oncology, Departments of Surgery and Radiation Oncology, UCLA School of Medicine, University of California, Los Angeles, and Surgical Service, Sepulveda Veterans Administration Medical Center, Sepulveda, California
Search for more papers by this authorRobert W. Rand MD, PhD
Divisions of Neurosurgery and Oncology, Departments of Surgery and Radiation Oncology, UCLA School of Medicine, University of California, Los Angeles, and Surgical Service, Sepulveda Veterans Administration Medical Center, Sepulveda, California
Search for more papers by this authorF. Kristian Storm MD
Divisions of Neurosurgery and Oncology, Departments of Surgery and Radiation Oncology, UCLA School of Medicine, University of California, Los Angeles, and Surgical Service, Sepulveda Veterans Administration Medical Center, Sepulveda, California
Search for more papers by this authorDonald L. Morton MD
Divisions of Neurosurgery and Oncology, Departments of Surgery and Radiation Oncology, UCLA School of Medicine, University of California, Los Angeles, and Surgical Service, Sepulveda Veterans Administration Medical Center, Sepulveda, California
Search for more papers by this authorAbstract
A rabbit brain tumor model is described using transplanted VX-2 carcinoma. The mean survival time after tumor transplantation was 9.3 days, and the reproducibility rate was 90%. In addition, this new model offers significant advantages over previously reported brain tumor models in terms of ease of induction and shortened latency times.
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