Volume 130, Issue 4 pp. 904-912
RESEARCH ARTICLE

Quality of Life Post Cervical Cancer Treatment: A Comparison Between Radical Surgery Approach and Radiotherapy and Chemotherapy

Alyne O. Tokarski

Corresponding Author

Alyne O. Tokarski

Medical Student in Pontifícia Universidade Católica do Paraná, Curitiba, Paraná, Brazil

Correspondence: Alyne O. Tokarski ([email protected])

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Rafaella S. Bernardelli

Rafaella S. Bernardelli

Assistant Professor at the School of Medicine at Pontifícia Universidade Católica do Paraná in the Department of Medical Scientific Initiation, Epidemiology, and Biostatistics, Curitiba, Paraná, Brazil

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Julia R. Bruscato

Julia R. Bruscato

Medical Student in Pontifícia Universidade Católica do Paraná, Curitiba, Paraná, Brazil

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Claudio R. Lucena

Claudio R. Lucena

Surgical Oncologist at Erasto Gaertner Hospital, Curitiba, Paraná, Brazil

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Jose C. Linhares

Jose C. Linhares

Head–Gynecologic Oncology Department at Erasto Gaertner Hospital, Curitiba, Paraná, Brazil

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Audrey T. Tsunoda

Audrey T. Tsunoda

Surgical Oncologist at Erasto Gaertner Hospital and at HCor and Assistant Professor at the School of Medicine at Pontifícia Universidade Católica do Paraná, Curitiba, Paraná, Brazil

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First published: 24 September 2024

ABSTRACT

Introduction

The assessment of quality of life (QoL) in women with cervical cancer is crucial due to the profound changes they undergo during and after treatment. Often, the significance of sexual factors is underestimated, likely due to societal taboos surrounding such discussions.

Objective

This study aimed to determine the long-term QoL outcomes, particularly focusing on sexuality, among three therapeutic approaches for cervical cancer: chemotherapy, radiotherapy, and brachytherapy; isolated hysterectomy; and hysterectomy combined with radiotherapy.

Methods

Conducted from November 2022 to July 2023, this cross-sectional study involved 131 cervical cancer patients. Their QoL was assessed using the MDASI, FACIT-Cx, and risk factor questionnaires. Results were compared across the three treatment groups, revealing notable differences.

Results

Patients undergoing chemo/radio/brachytherapy showed significantly lower QoL scores compared to those undergoing isolated hysterectomy. This was evident in reduced scores across FACIT-Cx subscales for physical well-being, specific concerns, and FACIT-total (p < 0.05). The MDASI results similarly indicated greater symptoms and interference in daily activities for the chemo/radio/brachytherapy group.

Conclusion

In conclusion, isolated hysterectomy, demonstrated superior QoL outcomes compared to chemo/radio/brachytherapy. Furthermore, the study underscored the importance of addressing sexual concerns in QoL assessments of cervical cancer survivors, emphasizing the need for comprehensive care to enhance overall well-being posttreatment.

Data Availability Statement

The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.

The full text of this article hosted at iucr.org is unavailable due to technical difficulties.