Volume 65, Issue 8 pp. 1255-1258
Note

Kinetics of acid neutralization by aluminum hydroxide gel

Steven L. Nail

Steven L. Nail

Industrial and Physical Pharmacy Department, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, IN 47907

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Joe L. White

Joe L. White

Department of Agronomy, Purdue University, West Lafayette, IN 47907

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Stanley L. Hem

Corresponding Author

Stanley L. Hem

Industrial and Physical Pharmacy Department, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, IN 47907

Industrial and Physical Pharmacy Department, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, IN 47907Search for more papers by this author
First published: August 1976
Citations: 3

Abstract

The rate of acid neutralization by an aluminum hydroxide gel prepared by the reaction of aluminum chloride solution and strong ammonia solution was studied. The decrease in acidconsuming capacity during aging as measured by the USP test is due to a decrease in the rate of reaction rather than to a decrease in equilibrium reactivity. The reactivity profile has three phases, which are shown to be related to the structure of the gel. The rate of loss of reactivity is directly related to the extent of washing.

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