Journal of Pharmaceutical Sciences
Volume 58, Issue 1 pp. 47-50
Research Article

Synthesis and antitussive activity of N-[indenyl(3)]ureas

T. George, 

T. George

Ciba Research Centre, Goregaon East, Bombay 63, India

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R. Tahilramani, 

R. Tahilramani

Ciba Research Centre, Goregaon East, Bombay 63, India

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C. L. Kaul, 

C. L. Kaul

Ciba Research Centre, Goregaon East, Bombay 63, India

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R. S. Grewal, 

R. S. Grewal

Ciba Research Centre, Goregaon East, Bombay 63, India

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First published: January 1969
https://doi.org/10.1002/jps.2600580107
Citations: 1

Abstract

Starting from indene, a variety of N-[indenyl(3)] ureas were synthesized and their pharmacological properties investigated. Several members of the series showed potent antitussive properties but also were found to possess a high order of toxicity.

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