Volume 20, Issue 6 pp. 418-431
Review

Past, present and future of atomic force microscopy in life sciences and medicine

Pierre Parot

Corresponding Author

Pierre Parot

CEA-Valrhô DSV/iBEB/SBTN, 30207 Bagnols sur Cèze Marcoule, France

DSV/iBEB/SBTN/LIRM, Service de Biochimie et Toxicologie Nucléaire/Laboratoire Interactions et Reconnaissance Moléculaires, CEA VALRHO Centre de Marcoule, BP 17171, 30207 Bagnols sur Cèze Cedex, France.Search for more papers by this author
Yves F. Dufrêne

Yves F. Dufrêne

Université catholique de Louvain, Louvain-la-Neuve, Belgium

Search for more papers by this author
Peter Hinterdorfer

Peter Hinterdorfer

Johannes Kepler Universitat Linz, Linz, Austria

Search for more papers by this author
Christian Le Grimellec

Christian Le Grimellec

Institut National de la Santé et de la Recherche Médicale, Unité 554, Montpellier, France and Université de Montpellier, France

Search for more papers by this author
Daniel Navajas

Daniel Navajas

Universitat de Barcelona—IDIBAPS and CIBER Enfermedades Respiratorias, Barcelona, Spain

Search for more papers by this author
Jean-Luc Pellequer

Jean-Luc Pellequer

CEA-Valrhô DSV/iBEB/SBTN, 30207 Bagnols sur Cèze Marcoule, France

Search for more papers by this author
Simon Scheuring

Simon Scheuring

Institut Curie, Paris, France

Search for more papers by this author
First published: 14 December 2007
Citations: 166

Abstract

To introduce this special issue of the Journal of Molecular Recognition dedicated to the applications of atomic force microscopy (AFM) in life sciences, this paper presents a short summary of the history of AFM in biology. Based on contributions from the first international conference of AFM in biological sciences and medicine (AFM BioMed Barcelona, 19–21 April 2007), we present and discuss recent progress made using AFM for studying cells and cellular interactions, probing single molecules, imaging biosurfaces at high resolution and investigating model membranes and their interactions. Future prospects in these different fields are also highlighted. Copyright © 2007 John Wiley & Sons, Ltd.

The full text of this article hosted at iucr.org is unavailable due to technical difficulties.