Reduction of the Michael addition products of anions of nitro compounds to dimethyl maleate led to the spontaneous formation of the respective 2-alkyl-5-oxopyrrolidine-3-carboxylic acid methyl esters. Conventional hydrolysis of the later gave the desired compounds.

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Volume45, Issue4

July/August 2008

Pages 1251-1253

Convenient preparations of 2-alkyl-5-oxopyrrolidine-3-carboxylic acids

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Convenient preparations of 2-alkyl-5-oxopyrrolidine-3-carboxylic acids

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