Volume 37, Issue 4 pp. 703-706

Article

Synthesis of 3-(4-Oxo-4H-quinolizinyl-3) and 3-(4-Oxo-4H-pyridino[1,2-a]pyrimidinyl-3) substituted lactic acid derivatives^†

Marko Škof,

Marko Škof

Faculty of Chemistry and Chemical Technology, University of Ljubljana, Aškerčeva 5, 1000 Ljubljana, Slovenia

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Jurij Svete,

Jurij Svete

Faculty of Chemistry and Chemical Technology, University of Ljubljana, Aškerčeva 5, 1000 Ljubljana, Slovenia

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Branko Stanovnik,

Branko Stanovnik

Faculty of Chemistry and Chemical Technology, University of Ljubljana, Aškerčeva 5, 1000 Ljubljana, Slovenia

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Marko Škof,

Marko Škof

Faculty of Chemistry and Chemical Technology, University of Ljubljana, Aškerčeva 5, 1000 Ljubljana, Slovenia

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Jurij Svete,

Jurij Svete

Faculty of Chemistry and Chemical Technology, University of Ljubljana, Aškerčeva 5, 1000 Ljubljana, Slovenia

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Branko Stanovnik,

Branko Stanovnik

Faculty of Chemistry and Chemical Technology, University of Ljubljana, Aškerčeva 5, 1000 Ljubljana, Slovenia

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First published: 11 March 2009

https://doi.org/10.1002/jhet.5570370405

Citations: 11

^†

Dedicated to the memory of the late Professor Raymond N. Castle

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Abstract

A one-step ‘ring switching’ transformation of (S)-3-[(dimethylamino)methylidene]-5-(methoxycarbonyl)tetrahydrofuran-2-one (4) with 2-pyridineacetic acid derivatives (5–7) and 2-aminopyridines (8, 9) afforded the corresponding 3-(4-oxo-4H-quinolizinyl-3)- (15–17) and 3-(4-oxo-4H-pyridino[1,2-a]pyrimidinyl-3)-2-hydroxypropanoates (18, 19), respectively.

References and Notes

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Volume37, Issue4

July/August 2000

Pages 703-706

Synthesis of 3-(4-Oxo-4H-quinolizinyl-3) and 3-(4-Oxo-4H-pyridino[1,2-a]pyrimidinyl-3) substituted lactic acid derivatives^†

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Synthesis of 3-(4-Oxo-4H-quinolizinyl-3) and 3-(4-Oxo-4H-pyridino[1,2-a]pyrimidinyl-3) substituted lactic acid derivatives†

Abstract

References and Notes

Citing Literature

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Synthesis of 3-(4-Oxo-4H-quinolizinyl-3) and 3-(4-Oxo-4H-pyridino[1,2-a]pyrimidinyl-3) substituted lactic acid derivatives^†