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3 The single contaminant was penicillin V methyl ester which arose from partial hydrolysis of 1 during work-up.
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6 The references which teach how to prepare 6b by this route are the following: (a) D. Thorne, West German Patent 1,927,692 (1969).
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Citing Literature

April 1975

Pages 445-447

Penicillin imino chlorides. II. A novel rearrangement leading to oxazoles