Volume 45, Issue 5 pp. 293-303

Research Article

Regression equations for calculation of z scores for echocardiographic measurements of right heart structures in healthy Han Chinese children

Shan-Shan Wang MD,

Shan-Shan Wang MD

Department of Pediatrics, Shanghai First Maternity and Infant Hospital, Tongji University, Shanghai, 201204 China

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Yu-Qi Zhang MD,

Corresponding Author

Yu-Qi Zhang MD

[email protected]

Department of Pediatric Cardiology, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, 200127 China

Correspondence to: Y.-Q. ZhangSearch for more papers by this author

Shu-Bao Chen MD,

Shu-Bao Chen MD

Department of Pediatric Cardiology, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, 200127 China

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Guo-Ying Huang MD,

Guo-Ying Huang MD

Department of Pediatric Cardiology, Children's Hospital of Fudan University, Shanghai, 201102 China

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Hong-Yan Zhang MD,

Hong-Yan Zhang MD

Department of Pediatric Cardiology, Tianjin Children's Hospital, Tianjin, 300204 China

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Zhi-Fang Zhang MD,

Zhi-Fang Zhang MD

Department of Pediatric Cardiology, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, 200127 China

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Lan-Ping Wu MD,

Lan-Ping Wu MD

Department of Pediatric Cardiology, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, 200127 China

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Wen-Jing Hong MD,

Wen-Jing Hong MD

Department of Pediatric Cardiology, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, 200127 China

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Rong Shen MD,

Rong Shen MD

Department of Pediatric Cardiology, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, 200127 China

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Yi-Qing Liu MD,

Yi-Qing Liu MD

Department of Pediatric Cardiology, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, 200127 China

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Jun-Xue Zhu MD,

Jun-Xue Zhu MD

Department of Pediatric Cardiology, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, 200127 China

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Shan-Shan Wang MD,

Shan-Shan Wang MD

Department of Pediatrics, Shanghai First Maternity and Infant Hospital, Tongji University, Shanghai, 201204 China

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Yu-Qi Zhang MD,

Corresponding Author

Yu-Qi Zhang MD

[email protected]

Department of Pediatric Cardiology, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, 200127 China

Correspondence to: Y.-Q. ZhangSearch for more papers by this author

Shu-Bao Chen MD,

Shu-Bao Chen MD

Department of Pediatric Cardiology, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, 200127 China

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Guo-Ying Huang MD,

Guo-Ying Huang MD

Department of Pediatric Cardiology, Children's Hospital of Fudan University, Shanghai, 201102 China

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Hong-Yan Zhang MD,

Hong-Yan Zhang MD

Department of Pediatric Cardiology, Tianjin Children's Hospital, Tianjin, 300204 China

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Zhi-Fang Zhang MD,

Zhi-Fang Zhang MD

Department of Pediatric Cardiology, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, 200127 China

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Lan-Ping Wu MD,

Lan-Ping Wu MD

Department of Pediatric Cardiology, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, 200127 China

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Wen-Jing Hong MD,

Wen-Jing Hong MD

Department of Pediatric Cardiology, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, 200127 China

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Rong Shen MD,

Rong Shen MD

Department of Pediatric Cardiology, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, 200127 China

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Yi-Qing Liu MD,

Yi-Qing Liu MD

Department of Pediatric Cardiology, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, 200127 China

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Jun-Xue Zhu MD,

Jun-Xue Zhu MD

Department of Pediatric Cardiology, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, 200127 China

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First published: 25 January 2017

https://doi.org/10.1002/jcu.22436

Citations: 4

This work was supported by the Shanghai Science and Technology Commission (Grant No. 10411965300) and the Innovation Program of Shanghai Municipal Education Commission (Grant No. 13ZZ081).

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ABSTRACT

Objective

Clinical decision making in children with congenital and acquired heart disease relies on measurements of cardiac structures using two-dimensional echocardiography. We aimed to establish z-score regression equations for right heart structures in healthy Chinese Han children.

Methods

Two-dimensional and M-mode echocardiography was performed in 515 patients. We measured the dimensions of the pulmonary valve annulus (PVA), main pulmonary artery (MPA), left pulmonary artery (LPA), right pulmonary artery (RPA), right ventricular outflow tract at end-diastole (RVOTd) and at end-systole (RVOTs), tricuspid valve annulus (TVA), right ventricular inflow tract at end-diastole (RVIDd) and at end-systole (RVIDs), and right atrium (RA). Regression analyses were conducted to relate the measurements of right heart structures to 4body surface area (BSA). Right ventricular outflow-tract fractional shortening (RVOTFS) was also calculated. Several models were used, and the best model was chosen to establish a z-score calculator.

Results

PVA, MPA, LPA, RPA, RVOTd, RVOTs, TVA, RVIDd, RVIDs, and RA (R² = 0.786, 0.705, 0.728, 0.701, 0.706, 0.824, 0.804, 0.663, 0.626, and 0.793, respectively) had a cubic polynomial relationship with BSA; specifically, measurement (M) = β0 + β1 × BSA + β2 × BSA² + β3 × BSA.³ RVOTFS (0.28 ± 0.02) fell within a narrow range (0.12–0.51).

Conclusions

Our results provide reference values for z scores and regression equations for right heart structures in Han Chinese children. These data may help interpreting the routine clinical measurement of right heart structures in children with congenital or acquired heart disease. © 2016 Wiley Periodicals, Inc. J Clin Ultrasound 45:293–303, 2017

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Volume45, Issue5

June 2017

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Regression equations for calculation of z scores for echocardiographic measurements of right heart structures in healthy Han Chinese children

ABSTRACT

Objective

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Conclusions

REFERENCES

Citing Literature

References

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Regression equations for calculation of z scores for echocardiographic measurements of right heart structures in healthy Han Chinese children

ABSTRACT

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