Volume 8, Issue 5 pp. 675-680
Editorial
Open Access

Oodles of opportunities: the Journal of Cachexia, Sarcopenia and Muscle in 2017

Stephan von Haehling

Corresponding Author

Stephan von Haehling

Department of Cardiology and Pneumology, University of Göttingen Medical Center, Göttingen, Germany

Correspondence to: Dr Stephan von Haehling, MD PhD FESC, Department of Cardiology and Pneumology, University of Göttingen Medical Center, Robert-Koch-Strasse 40, D-37075 Göttingen, Germany. Tel.: +49 551 39 20911; Fax: +49 551 39 20918. Email: [email protected]Search for more papers by this author
Nicole Ebner

Nicole Ebner

Department of Cardiology and Pneumology, University of Göttingen Medical Center, Göttingen, Germany

Search for more papers by this author
Stefan D. Anker

Stefan D. Anker

Division of Cardiology and Metabolism—Heart Failure, Cachexia & Sarcopenia, Department of Cardiology (CVK); and Berlin-Brandenburg Center for Regenerative Therapies (BCRT); Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK) Berlin, Charité Universitätsmedizin Berlin, Berlin, Germany

Search for more papers by this author
First published: 27 October 2017
Citations: 5

The good news first, the Journal of Cachexia, Sarcopenia and Muscle (JCSM) has not only maintained its impact factor, but it has even increased it again, now reaching 9.697 as has been published by Thomson Scientific a few weeks ago. To obtain a grip of the impact factor, it has to be acknowledged that it requires calculation of cites to items published in 2014 and 2015 divided by the number of items published in 2014 and 2015. In numbers, we reached a total of 368 cites in 2014 and 272 cites in 2015, summing up to 640 cites in total. This may not seem a lot, but considering that we only published 66 items deemed countable (editorial comments and letters-to-the-editor are not counted), the final impact factor reached 9.697, implying that each of our papers are cited almost 10 times over the course of 2 years. This places JCSM as the number 8 ranked journal among all journals in the category ‘Medicine, General and Internal’ (Table 1) and as number 2 ranking publication among all nutrition journals, among which, however, JCSM is still not officially listed by Thomson Scientific (Table 2).

As we have done before and are not getting tired of, we herewith express our gratitude to all authors, reviewers, and editorial board members for their great efforts to produce JCSM at good quality, and we greatly appreciate and value also the interest and support of all those who enjoy reading JCSM and cite the papers published there. Of course, the Journal would not be what it is without our editorial office team Monika Diek and Corinna Denecke, and we would also like to express our thanks for their professional support!

Table 1. Top 10 journals in the field ‘medicine: General & Internal’
Impact Items Issues
Journal name factor published per
2017 2015 and 2016 Year
1 New England Journal of Medicine 72.406 670 52
2 Lancet 47.831 646 52
3 Journal of the American Medical Association (JAMA) 44.405 410 48
4 British Medical Journal 20.785 446 52
5 Annals of Internal Medicine 17.135 150 24
6 JAMA Internal Medicine 16.538 275 12
7 PLOS Medicine 11.862 286 12
8 Journal of Cachexia, Sarcopenia and Muscle 9.697 88 4
9 BMC Medicine 7.901 418
10 Journal of Internal Medicine 7.598 194 12
Table 2. Top 10 journals in the field ‘Nutrition & Dietetics’, where the Journal of Cachexia, Sarcopenia and Muscle is officially not listed
Impact Items Issues
Journal name factor published per
2017 2015 and 2016 Year
1 Progress in Lipid Research 10.583 69 4
2 Annuals Review of Nutrition 9.054 44 1
3 American Journal of Clinical Nutrition 6.926 649 12
4 Critical Reviews in Food Science and Nutrition 6.077 149 12
5 International Journal of Obesity 5.487 502 12
6 Nutrition Reviews 5.291 132 12
7 Advances in Nutrition 5.233 177 6
8 Nutrition Research Reviews 4.844 29 2
9 Clinical Nutrition 4.548 375 6
10 Food Chemistry 4.529 3547 24

This year is special to JCSM for several reasons. One is the publication of additional issues this year, the other is the inauguration of our two daughter journals. Indeed, JCSM appears to have sparked more scientific interest in the field of body wasting, cachexia, and sarcopenia, and thus the number of submissions to the main journal remains on the increase. With a 73% rejection rate, we are well aware of the fact that we have to decline publication of many good papers, simply for lack of space. However, we do hope that we are able to give some of these a home in our daughter journals—JCSM Rapid Communications and JCSM Clinical Reports. The latter is online already since December 2016, and a good number of original research papers has been published since. At the time of writing this editorial in August 2017, the main journal, JCSM, has received already 187 submissions in 2017 alone, proving a steady increase in submissions: last year, this number was ‘only’ 158. Given these higher numbers of submissions, in 2017 we will move to six issues per year to allow publication of more accepted papers.

We are working hard to provide a timely peer review, which is not always easy, as it is difficult to find appropriate reviewers at times. Articles that are available for the longest time are—not surprisingly—those that have been cited most (Table 3). Our ‘facts and numbers’ editorials remain popular (Tables 4 and 5), and we invite our readers to submit their work or to suggest topics for ‘facts and numbers’ editorials that are relevant to our readers (Table 6).

Table 3. Top 10 of best cited articles since first publication of the Journal of Cachexia, Sarcopenia and Muscle
First Author Title Type Year Times Cited Reference
1 von Haehling Cachexia as a major underestimated and unmet medical need: facts and numbers Editorial 2010 203 1
2 von Haehling An overview of sarcopenia: facts and numbers on prevalence and clinical impact Editorial 2010 125 2
3 Dalton The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial Original article 2011 111 3
4 Morley From Sarcopenia to frailty: a road less travelled Editorial 2014 94 4
5 Lenk Skeletal muscle wasting in cachexia and sarcopenia: molecular pathophysiology and impact of exercise training Review 2010 90

5

6 Fanzani Molecular and cellular mechanisms of skeletal muscle atrophy: an update Review 2012 78 6
7 Elkina The role of myostatin in muscle wasting: an overview. Review 2011 75 7
8 Cesari Biomarkers of sarcopenia in clinical trials-recommendations from the International Working Group on Sarcopenia Original article 2012 72 8
9 Mak Wasting in chronic kidney disease Review 2011 67 9
10 von Haehling From muscle wasting to sarcopenia and myopenia: update 2012 Editorial 2012 63 10
Table 4. Top 20 of best cited articles published 2014 in the Journal of Cachexia, Sarcopenia and Muscle
First Author Title Type Times cited Reference
1 Wakabayashi Rehabilitation nutrition for sarcopenia with disability: a combination of both rehabilitation and nutrition care management Review 79 11
2 von Haehling Prevalence, incidence, and clinical impact of cachexia: facts and numbers—update 2014 Editorial 75 12
3 Morley Prevalence, incidence, and clinical impact of sarcopenia: facts, numbers, and epidemiology—update 2014 Editorial 69 13
4 Morley From sarcopenia to frailty: a road less travelled Editorial 59 4
5 Ormsbee Osteosarcopenic obesity: the role of bone, muscle, and fat on health Review 39 14
6 Heymsfield Assessing skeletal muscle mass: historical overview and state of the art Review 37 15
7 Morley Are we closer to having drugs to treat muscle wasting disease? Editorial 36 16
8 Anker Muscle wasting disease: a proposal for a new disease classification Editorial 27 17
9 Ebner Highlights from the 7th Cachexia Conference: muscle wasting pathophysiological detection and novel treatment strategies Meeting Report 26 18
10 Pietra Anamorelin HCl (ONO-7643), a novel ghrelin receptor agonist, for the treatment of cancer anorexia-cachexia syndrome: preclinical profile Original Article 26 19
11 Fragala Biomarkers of muscle quality: N-terminal propeptide of type III procollagen and C-terminal agrin fragment responses to resistance exercise training in older adults Original Article 25 20
12 Palus Muscle wasting: an overview of recent developments in basic research Review 20 21
13 Josiak Skeletal myopathy in patients with chronic heart failure: significance of anabolic-androgenic hormones Review 20 22
14 Toledo Formoterol in the treatment of experimental cancer cachexia: effects on heart function Original Article 19 23
15 Alchin Sarcopenia: describing rather than defining a condition Review 17 24
16 Argiles Cachexia: a problem of energetic inefficiency Review 16 25
17 Rhee Resistance exercise: an effective strategy to reverse muscle wasting in hemodialysis patients? Editorial 15 26
18 Khawaja Ventricular assist device implantation improves skeletal muscle function, oxidative capacity, and growth hormone/insulin-like growth factor-1 axis signalling in patients with advanced heart failure Original Article 15 27
19 Mirza Attenuation of muscle wasting in murine C2C12 myotubes by epigallocatechin-3-gallate Original Article 15 28
20 Kirkman Anabolic exercise in haemodialysis patients: a randomized controlled pilot study Original Article 13 29
Table 5. Top 20 of best cited articles published 2015 in the Journal of Cachexia, Sarcopenia and Muscle
First Author Title Type Times cited Reference
1 Calvani Biomarkers for physical frailty and sarcopenia: state of the science and future developments Review 37 30
2 Bowen Skeletal muscle wasting in cachexia and sarcopenia: molecular pathophysiology and impact of exercise training Review 36 31
3 Ezeoke Pathophysiology of anorexia in the cancer cachexia syndrome Review 28 32
4 Fearon Request for regulatory guidance for cancer cachexia intervention trials Editorial 24 33
5 Chen Ghrelin prevents tumour-induced and cisplatin-induced muscle wasting: characterization of multiple mechanisms involved Original Article 17 34
6 Manger Skeletal muscle alterations in chronic heart failure: differential effects on quadriceps and diaphragm Original Article 17 35
7 Grande Exercise for cancer cachexia in adults: Executive summary of a Cochrane Collaboration systematic review Review 16 36
8 Sasso A framework for prescription in exercise-oncology research Editorial 14 37
9 Cvan Trobec Influence of cancer cachexia on drug liver metabolism and renal elimination in rats Original Article 13 38
10 Dupuy Searching for a relevant definition of sarcopenia: results from the cross-sectional EPIDOS study Original Article 13 39
11 Morley Rapid screening for sarcopenia Editorial 12 40
12 Stephens Evaluating potential biomarkers of cachexia and survival in skeletal muscle of upper gastrointestinal cancer patients Original Article 11 41
13 Faber Improved body weight and performance status and reduced serum PGE2 levels after nutritional intervention with a specific medical food in newly diagnosed patients with esophageal cancer or adenocarcinoma of the gastro-esophageal junction Original Article 10 42
14 Drescher Loss of muscle mass: current developments in cachexia and sarcopenia focused on biomarkers and treatment Review 8 43
15 Wakabayashi Skeletal muscle mass is associated with severe dysphagia in cancer patients Original Article 8 44
16 Dev Hypermetabolism and symptom burden in advanced cancer patients evaluated in a cachexia clinic Original Article 6 45
17 Cooper Understanding and managing cancer-related weight loss and anorexia: insights from a systematic review of qualitative research Review 6 46
18 Marino Activin-βC modulates cachexia by repressing the ubiquitin-proteasome and autophagic degradation pathways Original Article 6 47
19 Haruta One-year intranasal application of growth hormone releasing peptide-2 improves body weight and hypoglycemia in a severely emaciated anorexia nervosa patient Original Article 5 48
20 van Norren Behavioural changes are a major contributing factor in the reduction of sarcopenia in caloric-restricted ageing mice Original Article 5 49
Table 6. Top 20 of best cited articles published 2016 in the Journal of Cachexia, Sarcopenia and Muscle
First Author Title Type Times cited Reference
1 Malmstrom SARC-F: a symptom score to predict persons with sarcopenia at risk for poor functional outcomes Original Article 33 50
2 Tyrovolas Factors associated with skeletal muscle mass, sarcopenia, and sarcopenic obesity in older adults: a multi-continent study Original Article 12 51
3 Sakuma p62/SQSTM1 but not LC3 is accumulated in sarcopenic muscle of mice Original Article 9 52
4 Loncar Cardiac cachexia: hic et nunc Review 8 53
5 Go Prognostic impact of sarcopenia in patients with diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone Original Article 6 54
6 de Lima Doxorubicin caused severe hyperglycaemia and insulin resistance, mediated by inhibition in AMPK signalling in skeletal muscle Original Article 6 55
7 Lodka Muscle RING-fingers 2 and 3 maintain striated-muscle structure and function Original Article 5 56
8 Lewis Increased expression of H19/miR-675 is associated with a low fat-free mass index in patients with COPD Original Article 5 57
9 Montano-Loza Sarcopenic obesity and myosteatosis are associated with higher mortality in patients with cirrhosis Original Article 4 58
10 Barbosa-Silva Prevalence of sarcopenia among community-dwelling elderly of a medium-sized South American city: results of the COMO VAI? study Original Article 4 59
11 Penna Effect of the specific proteasome inhibitor bortezomib on cancer-related muscle wasting Original Article 4 60
12 Vries Patient-centred physical therapy is (cost-) effective in increasing physical activity and reducing frailty in older adults with mobility problems: a randomized controlled trial with 6 months follow-up Original Article 4 61
13 Batista Cachexia-associated adipose tissue morphological rearrangement in gastrointestinal cancer patients Original Article 3 62
14 Giron Conversion of leucine to β-hydroxy-β-methylbutyrate by α-keto isocaproate dioxygenase is required for a potent stimulation of protein synthesis in L6 rat myotubes Original Article 3 63
15 Lainscak ACT-ONE-ACTION at last on cancer cachexia by adapting a novel action beta-blocker Editorial 3 64
16 Berger Dysfunction of respiratory muscles in critically ill patients on the intensive care unit Review 3 65
17 Musolino Megestrol acetate improves cardiac function in a model of cancer cachexia-induced cardiomyopathy by autophagic modulation Original Article 3 66
18 Neves White adipose tissue cells and the progression of cachexia: inflammatory pathways Original Article 2 67
19 Polge UBE2B is implicated in myofibrillar protein loss in catabolic C2C12 myotubes Original Article 2 68
20 Pinto Impact of creatine supplementation in combination with resistance training on lean mass in the elderly Original Article 2 69

Finally, we would like to draw attention to the upcoming Cachexia Conference to be held between December 8–10, 2017 in Rome, Italy. The conference became an annual meeting already 2 years ago, and it is a source of stimulating ideas and exchange between clinicians and researchers in the field of cachexia and wasting. Data on the final program and more information is to be found at http://society-scwd.org.

Acknowledgement

The authors certify that they comply with the ethical guidelines for authorship and publishing of the Journal of Cachexia, Sarcopenia and Muscle. 71

      The full text of this article hosted at iucr.org is unavailable due to technical difficulties.