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Update on the viral etiology of paget's disease of bone
Frederick R. Singer,
Corresponding Author
Frederick R. Singer
Endocrine/Bone Disease Program, John Wayne Cancer Institute, Santa Monica, California, U.S.A.
Frederick R. Singer, M.D. Director, Endocrine/Bone Disease Program John Wayne Cancer Institute at St. John's Medical Center 2200 Santa Monica Blvd. Santa Monica, CA 90404 U.S.A.Search for more papers by this authorFrederick R. Singer,
Corresponding Author
Frederick R. Singer
Endocrine/Bone Disease Program, John Wayne Cancer Institute, Santa Monica, California, U.S.A.
Frederick R. Singer, M.D. Director, Endocrine/Bone Disease Program John Wayne Cancer Institute at St. John's Medical Center 2200 Santa Monica Blvd. Santa Monica, CA 90404 U.S.A.Search for more papers by this author
References
- 1 Rebel A, Malkani K, Baslé M 1974 Anomalies nucleaires des osteoclasts de la maladie osseuse de Paget. Nouv Presse Med 3: 1299–1301.
- 2 Mills BG, Singer FR 1976 Nuclear inclusions in Paget's disease of bone. Science 194: 201–202.
- 3 Schulz A, Delling G, Ringe JD, Ziegler R 1977 Paget's disease of bone: Ultrastructure and cytogenesis of osteoclasts (author's transl). Virchows Arch a Pathol Anat 376: 309–328.
- 4 Gherardi G, Lo Cascio V, Bonucci E 1980 Fine structure of nuclei and cytoplasm of osteoclasts in Paget's disease of bone. Histopathology 4: 63–74.
- 5 Howatson AF, Fornasier VL 1982 Microfilaments associated with Paget's disease of bone: Comparison with nucleocapsids of measles virus and respiratory syncytial virus. Intervirology 18: 150–159.
- 6 Harvey L, Gray T, Beneton MN, Douglas DL, Kanis JA, Russell RG 1982 Ultrastructural features of the osteoclasts from Paget's disease of bone in relation to a viral aetiology. J Clin Pathol 35: 771–779.
- 7 Higo Y, Ohno T 1983 An ultrastructural study of osteoclasts in Paget's disease of bone. J Clin Electron Microscopy 16: 5–6.
- 8 Abe S, Ohno T, Park P, Higaki S, Unno K, Tateishi A 1995 Viral behavior of paracrystalline inclusions in osteoclasts of Paget's disease of bone. Ultrastruc Pathol 19: 455–461.
- 9 Mii Y, Miyauchi Y, Honoki K, Morishita T, Miura S, Aoki M, Tamai S, Tsunoda S, Nishitani M, Sakaki T 1994 Electron microscopic evidence of a viral nature for osteoclast inclusions in Paget's disease of bone. Virchows Arch a Pathol Anat 424: 99–104.
- 10 Dickinson GR, Shirodria PV, Kanis JA, Beneton MA, Carr KE, Mollan RA 1991 Familial expansile osteolysis: A morphological, histomorphometric and serological study. Bone 12: 331–338.
- 11 Welsh RA, Meyer AT 1970 Nuclear fragmentations and associated fibrils in giant cell tumor of bone. Lab Invest 22: 63–71.
- 12 Schajowicz F, Ubios AM, Aranjo ES, Cabrini RL 1985 Viruslike inclusions in giant cell tumor of bone. Clin Orthop 201: 247–250.
- 13 Abelanet R, Daudet-Monsac M, Laoussadi S, Forest M, Vacher-Lavenu MC 1986 Frequency and diagnostic value of the virus-like filamentous intranuclear inclusions in giant cell tumor of bone, not associated with Paget's disease. Virchows Arch a Pathol Anat 410: 65–68.
- 14 Beneton MNC, Harris SC, Kanis JA 1987 Paramyxovirus like inclusions in two cases of pycnodysostosis. Bone 8: 211–217.
- 15 Mills BG, Yabe H, Singer FR 1988 Osteoclasts in human osteopetrosis contain viral nucleocapsid-like nuclear inclusions. J Bone Miner Res 3: 101–106.
- 16 Bianco P, Silvestrini G, Ballanti P, Bonucci E 1992 Paramyxo-virus-like nuclear inclusions identical to those of Paget's disease detected in giant cells of primary oxalosis. Virchows Arch a Pathol Anat Histopathol 421: 427–433.
- 17 McKenna MJ, Mills BG, Galey FR, Linthicum FH Jr 1986 Filamentous structures morphologically similar to viral nucleocapsids in otosclerotic lesions in two patients. Am J Otol 7: 25–28.
- 18 Dubois-Dalccq M, Cablentz JM, Pleet AB 1974 Subacute sclerosing panencephalitis. Unusual nuclear inclusions and lengthy clinical course. Arch Neurol 31: 355–363.
- 19 Rebel A, Baslé M, Pouplard A, Kouyoundjian S, Filmon R, Lepatezour A 1980 Viral antigens in osteoclasts from Paget's disease of bone. Lancet 2: 344–346.
- 20 Baslé MF, Russell WC, Goswami KKA, Rebel A, Giraudon P, Wild F, Filmon R 1985 Paramyxovirus antigens in osteoclasts from Paget's bone tissue detected by monoclonal antibodies. J Gen Virol 66: 2103–2110.
- 21 Mills BG, Singer FR, Weiner LP, Suffin SC, Stabile E, Hoist P 1984 Evidence for both respiratory syncytial virus and measles virus antigens in the osteoclasts of patients with Paget's disease of bone. Clin Orthop 183: 303–311.
- 22 Mills BG, Singer FR, Weiner LP, Hoist PA 1981 Immunohistological demonstration of respiratory syncytial virus antigens in Paget's disease of bone. Proc Natl Acad Sci USA 78: 1209–1213.
- 23 Mills BG, Singer FR 1987 Critical evaluation of viral antigen data in Paget's disease of bone. Clin Orthop 217: 16–25
- 24 Nuovo MA, Nuovo GJ, Macconnell P, Forde A, Steiner GC 1992 In situ analyses of Paget's disease of bone for measles-specific PCR-amplified cDNA. Diagn Mol Pathol 1: 256–265.
- 25 Mills BG, Frausto A, Singer FR, Ohsaki Y, Demulder A, Roodman GD 1994 Multinucleated cells formed in vitro from Paget's bone marrow express viral antigens. Bone 15: 443–448.
- 26 Roodman GD, Ohsaki Y, Miller MM, Demulder A, Hosking D, Singer FR, McManus LM 1998 Pagetic osteoclasts formed in vitro: Absence of paracrystalline inclusions. J Submicrosc Cytol Pathol 30: 315–327.
- 27 McKenna MJ, Mills BG 1989 Immunochemical evidence of measles virus antigens in active otosclerosis. Otolaryngol Head Neck Surg 101: 415–421.
- 28 Baslé MF, Fournier JG, Rozenblatt S, Rebel A, Bouteille M 1986 Measles virus RNA detected in Paget's disease bone tissue by in situ hybridization. J Gen Virol 67: 907–913.
- 29 Gordon MT, Anderson DC, Sharpe PT 1991 Canine distemper virus localised in bone cells of patients with Paget's disease. Bone 12: 195–201.
- 30 Mee AP, Dixon JA, Hoyland JA, Davies M, Selby PL, Mawer EB 1998 Detection of canine distemper virus in 100% of Paget's disease samples by in situ-reverse transcriptase-polymerase reaction. Bone 23: 171–175.
- 31 Gordon MT, Mee AP, Anderson DC, Sharpe PT 1992 Canine distemper virus transcripts sequenced from pagetic bone. Bone Miner 19: 159–174.
- 32 Ralston SH, Digiovine FS, Gallagher SJ, Boyle IT, Duff GW 1991 Failure to detect paramyxovirus sequences in Paget's disease of bone using the polymerase chain reaction. J Bone Miner Res 6: 1243–1248.
- 33 Birch MA, Taylor W, Fraser WD, Ralston SH, Hart CA, Gallagher JA 1994 Absence of paramyxovirus RNA in cultures of pagetic bone cells and in pagetic bone. J Bone Miner Res 9: 11–16.
- 34 Reddy SV, Singer FR, Roodman GD 1995 Bone marrow mononuclear cells from patients with Paget's disease contain measles virus nucleocapsid messenger ribonucleic acid that has mutations in a specific region of the sequence. J Clin Endocrinol Metab 80: 2108–2111.
- 35 Reddy SV, Singer FR, Malette L, Roodman GD 1996 Detection of measles virus nucleocapsid transcripts in circulating blood cells from patients with Paget's disease. J Bone Miner Res 11: 1602–1607.
- 36 McKenna MJ, Kristiansen AG, Haines J 1996 Polymerase chain reaction amplification of a measles virus sequence from human temporal bone sections with active otosclerosis. Am J Otol 17: 827–830.
- 37 Swoveland PT, Johnson KP 1989 Subacute sclerosing panencephalitis and other paramyxovirus infections. In: RR McKendall, (ed.) Handbook of Clinical Neurology, Vol. 12. Elsevier Science Publishing Co, Inc., New York, NY, U.S.A., pp. 417–437.
- 38 Schmed Cattaneo A, Eschle D, Baczko K, ter Meulen V, Billeter MA 1988 Biased hypermutation and other genetic changes in defective measles viruses in human brain infections. Cell 55: 255–265.
- 39 Hirano A, Ayata M, Wang AH, Wong TC 1993 Functional analysis of matrix proteins expressed from cloned genes of measles virus variants that cause subacute sclerosing panencephalitis reveals a common defect in nucleocapsid binding. J Virol 67: 1848–1853.